Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113271 | 0.81 | HSD17B10 (0.74) | HSD17B10MAPK1ADORA2AADORA2BALDH1A1 | |
| SCHEMBL19590932 | 0.80 | ALDH1A1 (0.55) | MAPK1ALDH1A1CA12CA1CA2 | |
| SCHEMBL10113267 | 0.70 | HSD17B10 (0.72) | HSD17B10MAPK1ADORA2AADORA2BPOLB | |
| SCHEMBL10113385 | 0.68 | DHFR (0.79) | ADORA2BALDH1A1LMNAPOLBCA12 | |
| SCHEMBL5348761 | 0.68 | ALDH1A1 (0.47) | HSD17B10ALDH1A1LMNAPOLBTSHR | |
| SCHEMBL5342395 | 0.66 | ALDH1A1 (0.61) | MAPK1ALDH1A1LMNAPOLBTSHR | |
| SCHEMBL10113275 | 0.64 | ALDH1A1 (0.80) | MAPK1ALDH1A1CA12CA1CA2 | |
| SCHEMBL2999682 | 0.64 | ADORA2B (0.69) | HSD17B10MAPK1ADORA2AADORA2BALDH1A1 | |
| SCHEMBL2994443 | 0.64 | ADORA2B (0.75) | HSD17B10MAPK1ADORA2AADORA2B | |
| SCHEMBL8885844 | 0.63 | CACNA1D (0.57) | HSD17B10MAPK1ADORA2AADORA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815838-B2 | Methods and compositions for treating pain | HYDRA BIOSCIENCES, INC. (US) | 2017-11-14 | — | — | US | disclosed |