Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113261 | 0.78 | CYP3A4 (0.67) | CYP2C9CYP3A4CYP2C19ALOX12POLB | |
| SCHEMBL28342583 | 0.72 | TSHR (0.63) | CYP2C9CYP3A4CYP2C19ALOX12POLB | |
| SCHEMBL19752686 | 0.70 | POLB (1.00) | CYP2C9CYP3A4CYP2C19ALOX12POLB | |
| SCHEMBL19752684 | 0.70 | POLB (1.00) | CYP2C9CYP3A4CYP2C19ALOX12POLB | |
| SCHEMBL27937650 | 0.70 | ALDH1A1 (0.52) | CYP2C9CYP3A4CYP2C19ALOX12POLB | |
| SCHEMBL3017208 | 0.70 | CYP2C9 (0.73) | CYP2C9CYP3A4CYP2C19POLBTSHR | |
| SCHEMBL14164088 | 0.69 | CA1 (0.78) | CYP2C9CYP3A4CYP2C19ALOX12POLB | |
| SCHEMBL31706859 | 0.69 | CA1 (0.78) | CYP2C9CYP3A4CYP2C19ALOX12POLB | |
| SCHEMBL3031020 | 0.68 | ADORA3 (0.82) | CYP2C9CYP3A4CYP2C19ALOX12POLB | |
| SCHEMBL7380488 | 0.68 | CYP2C9 (0.57) | CYP2C9CYP3A4CYP2C19ALOX12POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815838-B2 | Methods and compositions for treating pain | HYDRA BIOSCIENCES, INC. (US) | 2017-11-14 | — | — | US | disclosed |