Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18459204 | 0.80 | CALM1 (0.55) | CYP11B1CYP11B2CYP3A4HRH3LTA4H | |
| SCHEMBL18459203 | 0.79 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP17A1CYP3A4CYP19A1 | |
| SCHEMBL25182373 | 0.78 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP17A1CYP3A4CYP19A1 | |
| SCHEMBL18459208 | 0.78 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP17A1CYP3A4CYP19A1 | |
| SCHEMBL721736 | 0.78 | CYP17A1 (0.61) | CYP11B1CYP11B2CYP17A1CYP3A4CYP19A1 | |
| SCHEMBL19841610 | 0.77 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP3A4CYP19A1 | |
| SCHEMBL753107 | 0.77 | GRM2 (0.41) | ALDH1A1MAPTSMN1; SMN2HPGDLOXL2 | |
| SCHEMBL13873567 | 0.75 | CYP17A1 (0.65) | CYP11B1CYP11B2CYP17A1CYP3A4CYP19A1 | |
| SCHEMBL19954367 | 0.75 | FLT1 (0.33) | CYP11B1CYP11B2LOXL2 | |
| SCHEMBL171160 | 0.75 | CYP17A1 (0.54) | CYP11B1CYP11B2CYP17A1CYP3A4CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9818960-B2 | Condensed cyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-11-14 | — | — | US | disclosed |