SCHEMBL753107

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752453	0.83	HTR2A (0.49)	GRM2TAAR1HTTMETAURKA
	SCHEMBL755263	0.82	GRM2 (0.42)	GRM2TAAR1HTTMETAURKA
	SCHEMBL25171202	0.79	NPC1 (0.39)	TAAR1HTTMETNPC1RAB9A
	SCHEMBL13218155	0.79	TRPA1 (0.38)	GRM2TAAR1METAURKAABL1
	SCHEMBL18459204	0.78	CALM1 (0.55)	TAAR1LMNA
	SCHEMBL19591007	0.77	CYP11B1 (0.49)	ALDH1A1HPGDMAPTLOXL2SMN1; SMN2
	SCHEMBL1468357	0.76	IDO1 (0.58)	TAAR1ALDH1A1LMNAIDO1LOXL2
	SCHEMBL16561361	0.76	IDO1 (0.58)	TAAR1ALDH1A1LMNAIDO1LOXL2
	SCHEMBL753048	0.76	MAOA (0.41)	GRM2TAAR1METNPC1RAB9A
	SCHEMBL756391	0.76	HTR2C (0.41)	GRM2METLMNAIDO1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.