⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28768963 | 0.97 | — | — | |
| SCHEMBL10717926 | 0.80 | ALDH1A1 (0.33) | — | |
| SCHEMBL10470845 | 0.72 | KIF11 (0.34) | — | |
| SCHEMBL3048564 | 0.62 | — | — | |
| SCHEMBL385899 | 0.62 | — | — | |
| SCHEMBL9215009 | 0.62 | — | — | |
| SCHEMBL129238 | 0.57 | — | — | |
| SCHEMBL2784059 | 0.57 | — | — | |
| SCHEMBL2039242 | 0.57 | — | — | |
| SCHEMBL1264108 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1923 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217913-A2 | PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND | HUA MEDICINE (SHANGHAI) LTD. (CN) | 2024-07-04 | — | — | US | claimed |
| WO-2024115549-A1 | ARYL- AND HETEROARYL-SULFONAMIDE DERIVATIVES AS CCR8 MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-06 | — | — | WO | claimed |
| CN-118026938-A | Pyrazolone ester compound and electrochemical synthesis method thereof | 江西本草天工科技有限责任公司 | 2024-05-14 | — | — | CN | claimed |
| CN-117623838-A | Chiral sulfoxide ester compound and preparation method thereof | 贵州大学 | 2024-03-01 | — | — | CN | claimed |
| CN-117327098-A | Preparation method and application of AIE type photosensitizer mainly used for type I photodynamic therapy | 江汉大学 | 2024-01-02 | — | — | CN | claimed |
| US-20230312455-A1 | PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND | HUA MEDICINE (SHANGHAI) LTD. (CN) | 2023-10-05 | — | — | US | claimed |
| CN-114085146-B | Preparation of substituted acrylate compounds | 华领医药技术（上海）有限公司 | 2023-09-01 | — | — | CN | claimed |
| US-20230257373-A1 | QUORUM SENSING INHIBITORS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH | 2023-08-17 | — | — | US | claimed |
| US-11702413-B2 | Organic semiconducting comonomer | PHILLIPS 66 COMPANY (US) | 2023-07-18 | — | — | US | claimed |
| EP-4206175-A1 | PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND | Hua Medicine (Shanghai) Ltd. (CN) | 2023-07-05 | — | — | EP | claimed |
| US-4822815-A | ANTAGONIZING ACTIONS OF THROMBOXANE A2 | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-04-18 | — | — | US | claimed |
| EP-0269968-A2 | Heteroaromatic amine derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-06-08 | — | — | EP | claimed |
| EP-0172031-B1 | NOVEL SULFENYLATED ACYLHYDRAZONES, COMPOSITIONS CONTAINING THEM, METHODS OF MAKING THEM AND THEIR USE | ROHM AND HAAS COMPANY (US) | 1988-05-18 | — | — | EP | claimed |
| EP-0228887-A2 | Dioxane hexenoic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-15 | — | — | EP | claimed |
| EP-0172031-A1 | Novel sulfenylated acylhydrazones, compositions containing them, methods of making them and their use | ROHM AND HAAS COMPANY (US) | 1986-02-19 | — | — | EP | claimed |
| US-4451659-A | Method of making known and previously unavailable pyrylium salts | RENSSELAER POLYTECHNIC INSTITUTE (US) | 1984-05-29 | — | — | US | claimed |
| EP-0097014-A2 | Triazole antifungal agents | Pfizer Limited (GB) | 1983-12-28 | — | — | EP | claimed |
| US-4199572-A | DERIVATIVES OF SISOMICINS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-04-22 | — | — | US | claimed |
| US-4025506-A | PENICILLINS | PFIZER INC. (US) | 1977-05-24 | — | — | US | claimed |
| US-4002616-A | POLYESTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-11 | — | — | US | claimed |