SCHEMBL195944

SCHEMBL195944

CCCCCN(CCC(=O)O)CC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 5/20 0.56
KDM4C Q9H3R0 3/20 0.56
PHF8 Q9UPP1 2/20 0.56
AKR1B1 P15121 1/20 0.52
GPR84 Q9NQS5 7/20 0.50
PPARG P37231 7/20 0.50
PPARD Q03181 7/20 0.50
PPARA Q07869 7/20 0.50
HDAC11 Q96DB2 5/20 0.50
TSHR P16473 5/20 0.50
PTPN1 P18031 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
ALDH1A1 P00352 2/20 0.50
TLR2 O60603 2/20 0.50
FABP4 P15090 2/20 0.50
ALOX15 P16050 2/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
SLC22A8 Q8TCC7 1/20 0.50
MEN1 O00255 1/20 0.50
ESR1 P03372 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27000037 0.98 KDM5A (0.58) KDM5AKDM4CPHF8AKR1B1GPR84
SCHEMBL16260781 0.98 KDM5A (0.58) KDM5AKDM4CPHF8AKR1B1GPR84
SCHEMBL1976352 0.92 TSHR (0.56) KDM5AKDM4CPHF8AKR1B1GPR84
SCHEMBL16260779 0.90 GPR84 (0.59) KDM5AKDM4CPHF8AKR1B1GPR84
SCHEMBL19040769 0.90 TSHR (0.54) KDM5AKDM4CPHF8AKR1B1GPR84
SCHEMBL19821298 0.90 TSHR (0.54) KDM5AKDM4CPHF8AKR1B1GPR84
SCHEMBL7568504 0.90 TSHR (0.54) KDM5AKDM4CPHF8AKR1B1GPR84
SCHEMBL6284898 0.90 KDM5A (0.66) KDM5AKDM4CPHF8AKR1B1GPR84
SCHEMBL8588942 0.90 TSHR (0.54) KDM5AKDM4CPHF8AKR1B1GPR84
SCHEMBL19821297 0.90 TSHR (0.54) KDM5AKDM4CPHF8AKR1B1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8060182-A None JP disclosed
US-20240199844-A1 SILICONE OIL COMPOUND FOR DEFOAMING AGENT AND DEFOAMING AGENT COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-06-20 US disclosed
EP-4324539-A1 SILICONE OIL COMPOUND FOR ANTIFOAMING AGENT AND ANTIFOAMING COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-02-21 EP disclosed
CN-117243830-A Hair cleansing composition and use thereof 北京仁生泽发生物技术有限公司 2023-12-19 CN disclosed
WO-2022220097-A1 SILICONE OIL COMPOUND FOR ANTIFOAMING AGENT AND ANTIFOAMING COMPOSITION 信越化学工業株式会社 2022-10-20 WO disclosed
EP-2641929-B1 NOVEL ORGANOPOLYSILOXANE, COSMETIC CONTAINING THEREOF, AND METHOD FOR PREPARING ORGANOPOLYSILOXANE SHINETSU CHEMICAL CO (JP) 2017-11-29 EP disclosed
EP-2662400-B1 Block type-modified organopolysiloxane, method for using the organopolysiloxane, cosmetic, and method for producing the organopolysiloxane SHINETSU CHEMICAL CO (JP) 2017-09-13 EP disclosed
US-20170000723-A1 ORGANOPOLYSILOXANE AND HAIR COSMETIC AND METHOD FOR PRODUCING THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-01-05 US disclosed
EP-3111923-A1 ORGANOPOLYSILOXANE AND HAIR COSMETIC AND METHOD FOR PRODUCING THEREOF Shin-Etsu Chemical Co., Ltd. (JP) 2017-01-04 EP disclosed
US-9109090-B2 Amino acid-modified organopolysiloxane, making method, and cosmetics SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-08-18 US disclosed
US-6793846-B2 Microbicide compositions KAO CORPORATION (JP) 2004-09-21 US disclosed
EP-1064845-B1 Virucidal and sporicidal composition KAO CORP (JP) 2003-09-10 EP disclosed
US-20030155549-A1 Microbicide compositions KAO CORPORATION (JP) 2003-08-21 US disclosed
US-20030138498-A1 Methods of sterilization KAO CORPORATION (JP) 2003-07-24 US disclosed
US-6506416-B1 Containing sodium percarbonate, sodium sulfate, tetraacetylethylenediamine and an alkaline earth salt KAO CORPORATION (JP) 2003-01-14 US disclosed
EP-1236399-A1 METHODS OF STERILIZATION Kao Corporation (JP) 2002-09-04 EP disclosed
EP-1236398-A1 MICROBICIDE COMPOSITIONS Kao Corporation (JP) 2002-09-04 EP disclosed
EP-1064845-A1 Virucidal and sporicidal composition Kao Corporation (JP) 2001-01-03 EP disclosed
EP-1065265-A1 Germicidal detergent composition Kao Corporation (JP) 2001-01-03 EP disclosed
JP-H0860182-A CLEANSING AGENT COMPOSITION KAO CORP 1996-03-05 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170000723-A1 ORGANOPOLYSILOXANE AND HAIR COSMETIC AND METHOD FOR PRODUCING THEREOF NR5A2, H1-5, H1-2 KDM5A 546/4885KDM4C 1525/4885PHF8 1354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.