Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.66 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2477376 | 0.94 | FFAR4 (0.73) | FFAR4MAOBMAOARAB9AKMT2A | |
| SCHEMBL1741575 | 0.89 | FFAR4 (0.67) | FFAR4MAOBMAOARAB9AKMT2A | |
| SCHEMBL7900785 | 0.85 | MAOB (0.75) | FFAR4MAOBMAOARAB9AKMT2A | |
| SCHEMBL4212043 | 0.85 | MAOB (0.58) | MAOBMAOARAB9AKMT2ANPC1 | |
| SCHEMBL1958139 | 0.82 | FFAR4 (0.75) | FFAR4NPC1MAPTFFAR1HPGD | |
| SCHEMBL28921334 | 0.81 | MAOB (0.51) | FFAR4MAOBMAOARAB9ANPC1 | |
| SCHEMBL22160289 | 0.80 | KMT2A (0.58) | FFAR4RAB9AKMT2ANPC1MAPT | |
| SCHEMBL12283379 | 0.80 | FFAR4 (0.54) | FFAR4MAOBRAB9ANPC1MAPT | |
| SCHEMBL109588 | 0.79 | CA12 (0.67) | FFAR4RAB9AKMT2ANPC1MAPT | |
| SCHEMBL29032389 | 0.78 | SMPD1 (0.53) | FFAR4RAB9AKMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507211-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011068560-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-06-09 | — | — | WO | disclosed |