SCHEMBL109588

SCHEMBL109588

COC(=O)c1ccc(F)cc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.67
CA1 P00915 4/20 0.67
CA2 P00918 4/20 0.67
CA7 P43166 4/20 0.67
CA9 Q16790 4/20 0.67
CA14 Q9ULX7 4/20 0.67
PDK2 Q15119 1/20 0.67
PDK4 Q16654 1/20 0.67
GAA P10253 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.57
TSHR P16473 2/20 0.55
LMNA P02545 1/20 0.55
MYC P01106 1/20 0.54
SLC6A4 P31645 1/20 0.49
SLC6A3 Q01959 1/20 0.49
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11690819 0.86 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL31258832 0.85 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL1367028 0.85 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL2708451 0.84 SLC6A4 (0.51) CA12CA1CA2CA7CA9
SCHEMBL30301996 0.84 SLC6A4 (0.51) CA12CA1CA2CA7CA9
SCHEMBL523258 0.82 CES2 (0.61) CA12CA1CA2CA7CA9
SCHEMBL14012584 0.82 CES2 (0.61) CA12CA1CA2CA7CA9
SCHEMBL25045978 0.81 GAA (0.52) CA12CA1CA2CA7CA9
SCHEMBL1097161 0.81 NPC1 (0.51) CA12CA1CA2CA7CA9
SCHEMBL23607068 0.81 SLC6A4 (0.49) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240115470-A1 METHYL-FLUORO-HYDROXYBENZOATES IN CONSUMER PRODUCTS SA, GIVAUDAN (CH) 2024-04-11 US claimed
EP-4259082-A1 METHYL-FLUORO-HYDROXYBENZOATES IN CONSUMER PRODUCTS Givaudan SA (CH) 2023-10-18 EP claimed
WO-2022122836-A1 METHYL-FLUORO-HYDROXYBENZOATES IN CONSUMER PRODUCTS GIVAUDAN SA (CH) 2022-06-16 WO claimed
CN-107235978-B A kind of preparation method of ABT-199 intermediate 上海泓博智源医药股份有限公司 2019-05-21 CN claimed
CN-107235978-A A kind of preparation method of the intermediates of ABT 199 上海泓博智源医药股份有限公司 2017-10-10 CN claimed
US-20260132112-A1 COMPOUNDS CTXT PTY LTD (AU) 2026-05-14 US disclosed
US-12617780-B2 Benzothiophene, thienopyridine and thienopyrimidine derivatives for the modulation of sting CTXT PTY LTD (AU) 2026-05-05 US disclosed
EP-4720038-A1 (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES Neophore Limited (GB) 2026-04-08 EP disclosed
US-20260092057-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-02 US disclosed
US-20250377364-A1 REAGENT, METHOD, AND DEVICE FOR DETECTING ALBUMIN NEC CORPORATION (JP) 2025-12-11 US disclosed
EP-4638460-A1 BENZIMIDAZOLE DERIVATIVES FOR THE MODULATION OF STING Aculeus Therapeutics Pty Ltd (AU) 2025-10-29 EP disclosed
EP-4077318-B1 BENZIMIDAZOLE DIMERS AS MODULATORS OF STING CTXT PTY LTD (AU) 2025-10-15 EP disclosed
EP-1424336-A1 1,3-BENZOTHIAZINONE DERIVATIVES AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2004-06-02 EP disclosed
US-20040058959-A1 Substituted carboxamides HERRON DAVID KENT (US) 2004-03-25 US disclosed
WO-2004005295-A1 NOVEL TRICYCLIC SPIROPIPERIDINES OR SPIROPYRROLIDINES ASTRAZENECA AB (SE) 2004-01-15 WO disclosed
EP-1379506-A2 SUBSTITUTED CARBOXAMIDES ELI LILLY AND COMPANY (US) 2004-01-14 EP disclosed
EP-1373248-A1 BENZIMIDAZOL DERIVATIVES MODULATE CHEMOKINE RECEPTORS AstraZeneca AB (SE) 2004-01-02 EP disclosed
WO-2002074763-A9 BENZIMIDAZOL DERIVATIVES MODULATE CHEMOKINE RECEPTORS ASTRAZENECA AB (SE) 2002-10-24 WO disclosed
WO-2002074763-A1 BENZIMIDAZOL DERIVATIVES MODULATE CHEMOKINE RECEPTORS ASTRAZENECA AB (SE) 2002-09-26 WO disclosed
WO-2002064567-A2 SUBSTITUTED CARBOXAMIDES AS INHIBITORS OF FACTOR XA ELI LILLY AND COMPANY (US) 2002-08-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250377364-A1 REAGENT, METHOD, AND DEVICE FOR DETECTING ALBUMIN ALB, TTR, MTTP CA12 367/4885CA1 1488/4885CA2 3341/4885
US-20260092057-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF BCL2L2, BCL2A1, BCL2L1 CA12 1371/4885CA1 436/4885CA2 323/4885
US-20260132112-A1 COMPOUNDS STING1, IRF3, CGAS CA12 1419/4885CA1 1434/4885CA2 2353/4885
US-20240115470-A1 METHYL-FLUORO-HYDROXYBENZOATES IN CONSUMER PRODUCTS KDM5B, FOSB, KDM2B CA12 2279/4885CA1 3577/4885CA2 2648/4885
US-12617780-B2 Benzothiophene, thienopyridine and thienopyrimidine derivatives for the modulation of sting STING1, CGAS, IRF3 CA12 3837/4885CA1 3784/4885CA2 2504/4885
US-20040058959-A1 Substituted carboxamides F11, F12, TFPI CA12 374/4885CA1 852/4885CA2 1037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.