SCHEMBL1959604

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3595619	0.91	GPR119 (0.56)	MAPTLMNAALDH1A1GPR119BCL2
	SCHEMBL2944141	0.88	MAPT (0.51)	MAPTGAALMNAALDH1A1HTT
	SCHEMBL28131741	0.86	MAPT (0.53)	MAPTGAALMNAALDH1A1HTT
	SCHEMBL22581464	0.83	MAPT (0.50)	MAPTGAALMNAALDH1A1HTT
	SCHEMBL30414834	0.83	MAPT (0.50)	MAPTGAALMNAALDH1A1HTT
	SCHEMBL1700248	0.83	MAPT (0.53)	MAPTGAALMNAALDH1A1HTT
	SCHEMBL550289	0.83	ALDH1A1 (0.49)	MAPTLMNAALDH1A1HTTGPR119
	SCHEMBL2952145	0.82	BCL2L1 (0.52)	MAPTGAALMNAALDH1A1HTT
	SCHEMBL31344646	0.82	MAPT (0.52)	MAPTGAALMNAALDH1A1HTT
	SCHEMBL1700051	0.82	MAPT (0.52)	MAPTGAALMNAALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.