SCHEMBL19598951

SCHEMBL19598951

Cc1ccc2c(c1)C1C(=O)CC(=O)C1CC2C1CC(=O)OC1=O

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
ALDH2 P05091 1/20 0.37
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
THRB P10828 2/20 0.33
GAA P10253 1/20 0.32
HPGD P15428 2/20 0.31
GLA P06280 1/20 0.31
RECQL P46063 1/20 0.31
SIRT2 Q8IXJ6 3/20 0.31
TERT O14746 1/20 0.30
HTR2C P28335 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29394478 0.86 ALDH1A1 (0.39) ALDH1A1ALDH2MEN1MAPTKMT2A
SCHEMBL351607 0.86 ALDH1A1 (0.39) ALDH1A1ALDH2MEN1MAPTKMT2A
SCHEMBL13569483 0.84 ALDH1A1 (0.39) ALDH1A1MAPTHPGD
SCHEMBL12172584 0.83 ALDH1A1 (0.32) ALDH1A1KMT2A
SCHEMBL352092 0.81 ALDH1A1 (0.39) ALDH1A1ALDH2MEN1MAPTKMT2A
SCHEMBL29340226 0.77 ALDH1A1 (0.36) ALDH1A1ALDH2MEN1MAPTKMT2A
SCHEMBL31486511 0.75 ALDH1A1 (0.37) ALDH1A1ALDH2MEN1MAPTKMT2A
SCHEMBL4341363 0.73 ALDH1A1 (0.38) ALDH1A1ALDH2MEN1MAPTKMT2A
SCHEMBL19751806 0.72 ALDH1A1 (0.32) ALDH1A1
SCHEMBL13357975 0.71 ALDH1A1 (0.34) ALDH1A1ALDH2MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10437149-B2 Photosensitive resin composition, planographic printing plate precursor, method for producing planographic printing plate, and polymer compound FUJIFILM CORPORATION (JP) 2019-10-08 US disclosed
US-20170329225-A1 PHOTOSENSITIVE RESIN COMPOSITION, PLANOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE, AND POLYMER COMPOUND FUJIFILM CORPORATION (JP) 2017-11-16 US disclosed
US-20170329225-A1 PHOTOSENSITIVE RESIN COMPOSITION, PLANOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE, AND POLYMER COMPOUND FUJIFILM CORPORATION (JP) 2017-11-16 US disclosed