SCHEMBL352092

SCHEMBL352092

Cc1ccc2c(c1)C(C1CC(=O)OC1=O)CC1C(=O)OC(=O)C21

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
ALDH2 P05091 1/20 0.39
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
THRB P10828 2/20 0.35
HTR2C P28335 2/20 0.33
GAA P10253 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2B P41595 1/20 0.33
HPGD P15428 2/20 0.33
GLA P06280 1/20 0.33
RECQL P46063 1/20 0.33
SIRT2 Q8IXJ6 5/20 0.32
TERT O14746 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL351607 0.95 ALDH1A1 (0.39) ALDH1A1ALDH2MEN1MAPTKMT2A
SCHEMBL29394478 0.95 ALDH1A1 (0.39) ALDH1A1ALDH2MEN1MAPTKMT2A
SCHEMBL29340226 0.90 ALDH1A1 (0.36) ALDH1A1ALDH2MEN1MAPTKMT2A
SCHEMBL351239 0.83
SCHEMBL23395844 0.81 ALDH1A1 (0.31) ALDH1A1MEN1MAPTKMT2ATHRB
SCHEMBL257601 0.81 ALDH1A1 (0.31) ALDH1A1MEN1MAPTKMT2ATHRB
SCHEMBL15935547 0.81 ALDH1A1 (0.31) ALDH1A1MEN1MAPTKMT2ATHRB
SCHEMBL29353334 0.81 ALDH1A1 (0.31) ALDH1A1MEN1MAPTKMT2ATHRB
SCHEMBL19598951 0.81 ALDH1A1 (0.37) ALDH1A1ALDH2MEN1MAPTKMT2A
SCHEMBL12110806 0.80 SIRT2 (0.31) SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718666-B1 Liquid crystal-aligning agent JSR CORP (JP) 2003-03-26 EP claimed
EP-0725302-B1 A process of producing a polyimide block copolymer JAPAN SYNTHETIC RUBBER CO LTD (JP) 2002-04-03 EP claimed
US-5773559-A POLYAMIC ACID, POLYIMIDE BLOCK POLYMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-30 US claimed
US-5698135-A POLYAMIC ACID OBTAINED FROM REACTION OF DIANHYDRIDE OF SPECIFIED TETRACARBOXYLIC ACID AND OF CYCLOBUTANETETRACARBOXYLIC ACID WITH DIAMINE, OR POLYMER OBTAINED BY IMIDIZING SAID POLYAMIC ACID JAPAN SYNTHETIC RUBBER CO., LTD., A JAPANESE CORPORATION (JP) 1997-12-16 US claimed
EP-0718666-A1 Liquid crystal-aligning agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-26 EP claimed
EP-2375278-B1 COMPOSITION FOR FORMING LIQUID CRYSTAL ALIGNMENT FILM SHARP KK (JP) 2020-04-08 EP disclosed
US-10131842-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-11-20 US disclosed
US-10100254-B2 Liquid crystal alignment agent and liquid crystal alignment film and liquid crystal display element formed from the liquid crystal alignment agent CHI MEI CORPORATION (TW) 2018-10-16 US disclosed
US-10100255-B2 Liquid crystal alignment agent and liquid crystal alignment film and liquid crystal display element formed from the liquid crystal alignment agent CHI MEI CORPORATION (TW) 2018-10-16 US disclosed
US-10082704-B2 Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element having thereof CHI MEI CORPORATION (TW) 2018-09-25 US disclosed
US-10000702-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-06-19 US disclosed
US-9976088-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element having the same CHI MEI CORPORATION (TW) 2018-05-22 US disclosed
US-5969055-A MIXTURES OF POLYAMIC ACIDS AND IMIDIZED POLYMERS FROM THE DEHYDRATION AND RING CLOSURE OF POLYAMIC ACID, THE POLYMERS HAVING HIGHER IMIDIZATION DEGREE ALSO HAVE SMALLER SURFACE FREE ENERGY, FILMS, HIGH PRETILT ANGLE, LOW IMAGE RETENTION JSR CORPORATION (JP) 1999-10-19 US disclosed
EP-0875781-A2 Liquid crystal alignment layer, production method for the same, and liquid crystal display device comprising the same JSR Corporation (JP) 1998-11-04 EP disclosed
US-5773559-A POLYAMIC ACID, POLYIMIDE BLOCK POLYMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-30 US disclosed
EP-0840161-A1 LIQUID CRYSTAL ALIGNING AGENT JSR Corporation (JP) 1998-05-06 EP disclosed
US-5700860-A Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-23 US disclosed
US-5698135-A POLYAMIC ACID OBTAINED FROM REACTION OF DIANHYDRIDE OF SPECIFIED TETRACARBOXYLIC ACID AND OF CYCLOBUTANETETRACARBOXYLIC ACID WITH DIAMINE, OR POLYMER OBTAINED BY IMIDIZING SAID POLYAMIC ACID JAPAN SYNTHETIC RUBBER CO., LTD., A JAPANESE CORPORATION (JP) 1997-12-16 US disclosed
EP-0735403-A1 Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-10-02 EP disclosed
EP-0718666-A1 Liquid crystal-aligning agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-26 EP disclosed