SCHEMBL7735555

SCHEMBL7735555

O=C1c2cccc3c(Cl)ccc(c23)C(=O)N1CCO

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.68
ALDH1A1 P00352 4/20 0.68
LMNA P02545 3/20 0.68
MAPT P10636 4/20 0.65
CYP1A2 P05177 2/20 0.65
HPGD P15428 2/20 0.65
POLB P06746 1/20 0.65
ERCC1 P07992 1/20 0.65
TSHR P16473 1/20 0.65
ALOX12 P18054 1/20 0.65
FEN1 P39748 1/20 0.65
ERCC4 Q92889 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
HEXA P06865 1/20 0.62
HEXB P07686 1/20 0.62
KMT2A Q03164 6/20 0.61
MEN1 O00255 5/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
AVPR1A P37288 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6885854 0.89 KDM4E (0.63) KDM4EALDH1A1LMNAMAPTCYP1A2
SCHEMBL10262050 0.86 LMNA (0.59) KDM4EALDH1A1LMNAMAPTCYP1A2
SCHEMBL11629372 0.86 KDM4E (0.70) KDM4EALDH1A1LMNAMAPTCYP1A2
SCHEMBL17733959 0.85 KDM4E (0.68) KDM4EALDH1A1LMNAMAPTCYP1A2
SCHEMBL17726925 0.85 ALDH1A1 (0.78) KDM4EALDH1A1LMNAMAPTCYP1A2
SCHEMBL10717566 0.84 ALDH1A1 (0.56) KDM4EALDH1A1LMNAMAPTCYP1A2
SCHEMBL9952436 0.84 KDM4E (0.63) KDM4EALDH1A1LMNAMAPTCYP1A2
SCHEMBL10267893 0.84 ALDH1A1 (0.77) KDM4EALDH1A1LMNAMAPTCYP1A2
SCHEMBL338647 0.84 KDM4E (0.67) KDM4EALDH1A1LMNAMAPTCYP1A2
SCHEMBL11256119 0.83 MEN1 (0.65) KDM4EALDH1A1LMNAMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322966-A1 Photopolymerizable Compositions Including a Polyurethane Methacrylate Polymer Prepared Using a Polycarbonate Diol, Articles, and Methods SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-10-12 US disclosed
US-20230322966-A1 Photopolymerizable Compositions Including a Polyurethane Methacrylate Polymer Prepared Using a Polycarbonate Diol, Articles, and Methods SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-10-12 US disclosed
US-11708428-B2 Photopolymerizable compositions including a polyurethane methacrylate polymer prepared using a polycarbonate diol, articles, and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-25 US disclosed
US-11708428-B2 Photopolymerizable compositions including a polyurethane methacrylate polymer prepared using a polycarbonate diol, articles, and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-25 US disclosed
US-11225535-B2 Photopolymerizable compositions including a polyurethane methacrylate polymer prepared using a polycarbonate diol, articles, and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-01-18 US disclosed
US-20210355262-A1 ORTHODONTIC ARTICLES PREPARED USING A POLYCARBONATE DIOL, AND METHODS OF MAKING SAME 3M INNOVATIVE PROPERTIES COMPANY 2021-11-18 US disclosed
US-20210301042-A1 PHOTOPOLYMERIZABLE COMPOSITIONS INCLUDING A POLYURETHANE METHACRYLATE POLYMER PREPARED USING A POLYCARBONATE DIOL, ARTICLES, AND METHODS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2021-09-30 US disclosed
US-20210171701-A1 ORTHODONTIC ARTICLES PREPARED USING A POLYCARBONATE DIOL, POLYMERIZABLE COMPOSITIONS, AND METHODS OF MAKING THE ARTICLES SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2021-06-10 US disclosed
US-20210163664-A1 ORTHODONTIC ARTICLES PREPARED USING A POLYCARBONATE DIOL, AND METHODS OF MAKING SAME SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2021-06-03 US disclosed
US-20210095056-A1 PHOTOPOLYMERIZABLE COMPOSITIONS INCLUDING A POLYURETHANE METHACRYLATE POLYMER PREPARED USING A POLYCARBONATE DIOL, ARTICLES, AND METHODS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2021-04-01 US disclosed
US-6248457-B1 ELECTROLUMINESCENT COPOLYMER WHICH CONTAINS REPEAT UNITS WITH PHOTOLUMINESCENT RESIDUES BAYER AG (DE) 2001-06-19 US disclosed
US-6114463-A Copolymers based on vinyl units and their use in electroluminescent devices BAYER AG (DE) 2000-09-05 US disclosed
US-6075106-A (Co)polymers based on vinyl units and use thereof in electroluminescent devices D-51368 BAYER AG (DE) 2000-06-13 US disclosed
US-5905128-A (CO) polymers based on vinyl units and use thereof in electroluminescent arrangements BAYER AG (DE) 1999-05-18 US disclosed
US-5891975-A (Co)polymers based on vinyl units and use thereof in electroluminescent devices BAYER AKTIENGESELLSCHAFT (DE) 1999-04-06 US disclosed
US-5807945-A (Co)polymers based on vinyl units and use thereof in electroluminescent arrangements BAYER AG (DE) 1998-09-15 US disclosed
CN-1151992-A (Co) polymers based on vinyl units and use thereof in electroluminescent arrangements BAYER AG (DE) 1997-06-18 CN disclosed
CN-1142510-A (Co) polymers based on vinyl units and use thereof in electroluminescent devices BAYER AG (DE) 1997-02-12 CN disclosed
CN-1140725-A (CO) polymers based on vinyl units and use thereof in electroluminescent decices BAYER AG (DE) 1997-01-22 CN disclosed
CN-1138036-A 1,8-naphthalimide derviatives, processes for their manufacture and use as intermediates BAYER AG (DE) 1996-12-18 CN disclosed