SCHEMBL1960073

SCHEMBL1960073

CC(C)(C)c1cc(CSCc2ccc(O)c(C(C)(C)C)c2)ccc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.53
ALOX15 P16050 6/20 0.53
LMNA P02545 4/20 0.53
CYP2C9 P11712 2/20 0.53
HSD17B10 Q99714 2/20 0.53
NR1I2 O75469 1/20 0.53
MIF P14174 1/20 0.53
TYR P14679 1/20 0.53
HTT P42858 1/20 0.53
NFE2L2 Q16236 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.46
CYP1A2 P05177 2/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ATP2A2 P16615 1/20 0.46
ATP2A3 Q93084 1/20 0.46
HSP90AA1 P07900 2/20 0.42
HSP90AB1 P08238 2/20 0.42
TSHR P16473 4/20 0.42
TDP1 Q9NUW8 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11548266 0.87 ALDH1A1 (0.52) ALDH1A1ALOX15LMNACYP2C9HSD17B10
SCHEMBL27386603 0.85 GAA (0.44) ALDH1A1ALOX15LMNACYP2C9HSD17B10
SCHEMBL7185376 0.83 TYR (0.41) ALDH1A1ALOX15LMNACYP2C9HSD17B10
SCHEMBL7199857 0.82 ALDH1A1 (0.59) ALDH1A1ALOX15LMNACYP2C9HSD17B10
SCHEMBL2919862 0.82 ALDH1A1 (0.59) ALDH1A1ALOX15LMNACYP2C9HSD17B10
SCHEMBL31146612 0.82 ALDH1A1 (0.59) ALDH1A1ALOX15LMNACYP2C9HSD17B10
SCHEMBL29836278 0.82 ALDH1A1 (0.59) ALDH1A1ALOX15LMNACYP2C9HSD17B10
SCHEMBL29603473 0.80 TRPA1 (0.59) ALDH1A1ALOX15LMNACYP2C9HSD17B10
SCHEMBL5175624 0.80 ALDH1A1 (0.57) ALDH1A1ALOX15LMNACYP2C9HSD17B10
SCHEMBL245857 0.80 TRPA1 (0.59) ALDH1A1ALOX15LMNACYP2C9HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053117-B1 LUBRICANT COMPOSITION IDEMITSU KOSAN CO (JP) 2020-10-28 EP disclosed
EP-2873721-B1 LUBRICATING OIL COMPOSITION AND AUTOMOTIVE TRANSMISSION OIL USING SAME IDEMITSU KOSAN CO (JP) 2020-09-02 EP disclosed
EP-2837677-B1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN CO (JP) 2019-09-18 EP disclosed
EP-2443160-B1 OLIGOMERIZATION OF ALPHA OLEFINS USING METALLOCENE-SSA CATALYST SYSTEMS AND USE OF THE RESULTANT POLYALPHAOLEFINS TO PREPARE LUBRICANT BLENDS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-08-14 EP disclosed
CN-104293497-B Cleaning solution composition and method for cleaning substrate 奇美实业股份有限公司 2018-08-31 CN disclosed
US-9745230-B2 Oligomerization of alpha olefins using metallocene-SSA catalyst systems and use of the resultant polyalphaolefins to prepare lubricant blends CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2017-08-29 US disclosed
EP-2392637-B1 LUBRICATING OIL COMPOSITION FOR AUTOMATIC TRANSMISSION IDEMITSU KOSAN CO (JP) 2017-08-09 EP disclosed
US-9624453-B2 Lubricating oil composition and automotive transmission oil using same IDEMITSU KOSAN CO., LTD. (JP) 2017-04-18 US disclosed
US-9458402-B2 Lubricating oil composition IDEMITSU KOSAN CO., LTD. (JP) 2016-10-04 US disclosed
US-20160264493-A1 Oligomerization of Alpha Olefins Using Metallocene-SSA Catalyst Systems and Use of the Resultant Polyalphaolefins to Prepare Lubricant Blends CHEVRON PHILLIPS CHEMICAL COMPANY LP 2016-09-15 US disclosed
EP-2053117-A1 LUBRICANT COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2009-04-29 EP disclosed
US-20090069204-A1 LUBRICANT FOR OIL RETAINING BEARING IDEMITSU KOSAN CO., LTD. (JP) 2009-03-12 US disclosed
CN-101275089-A Method for improving oxidation stability of biodiesel CHINA PETROCHEMICAL CORP (CN) 2008-10-01 CN disclosed
US-20080234151-A1 Lubricating Oil Composition for Sizing Pressing IDEMITSU LOSAN CO., LTD. (JP) 2008-09-25 US disclosed
EP-1950277-A1 TRANSMISSION FLUID COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2008-07-30 EP disclosed
US-20070167343-A1 neutralized salt including alkylbenzenesulphonates (toluenesulfonic acid guanidine salt, toluenesulfonic acid DBU salt, toluenesulfonic acid DBN salt) for cleaning electonics SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2007-07-19 US disclosed
US-20070149416-A1 Lubricating oil composition for working using sizing press IDEMITSU KOSAN CO., LTD. (JP) 2007-06-28 US disclosed
US-20070037715-A1 LUBRICATING OIL COMPOSITION AND OIL-IMPREGNATED BEARING USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-02-15 US disclosed
US-20060199747-A1 Conductive lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2006-09-07 US disclosed
EP-1609844-A1 CONDUCTIVE LUBRICANT COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2005-12-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160264493-A1 Oligomerization of Alpha Olefins Using Metallocene-SSA Catalyst Systems and Use of the Resultant Polyalphaolefins to Prepare Lubricant Blends SAE1, MACO1, MSMO1 ALDH1A1 1229/4885ALOX15 17/4885LMNA 2545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.