Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25930328 | 0.89 | TSHR (0.40) | PPARATSHRMAPK1CYP1A2CYP2C9 | |
| SCHEMBL25603628 | 0.88 | PPARA (0.52) | PPARATSHRMAPK1SMN1; SMN2PPARG | |
| SCHEMBL19600789 | 0.86 | PPARA (0.53) | PPARATSHRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL19598756 | 0.85 | PPARA (0.45) | PPARATSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL19580810 | 0.81 | L3MBTL1 (0.41) | MAPK1SMN1; SMN2ALDH1A1TDP1NPC1 | |
| SCHEMBL18256139 | 0.80 | PPARA (0.43) | PPARATSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21405110 | 0.79 | L3MBTL1 (0.40) | PPARAMAPK1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL25602002 | 0.79 | SMPD1 (0.47) | PPARATSHRMAPK1CYP1A2CYP2C9 | |
| SCHEMBL19600794 | 0.79 | PPARA (0.47) | PPARATSHRMAPK1CYP1A2CYP2C9 | |
| SCHEMBL19600791 | 0.76 | GAA (0.36) | PPARATSHRCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327469-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | ARVINAS OPERATIONS, INC. | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327469-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | AR, MDM2, ESRRA | PPARA 1884/4885TSHR 1939/4885MAPK1 4210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.