Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25601889 | 0.82 | KLK7 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL25930328 | 0.80 | TSHR (0.40) | ALDH1A1TSHRTP53SMN1; SMN2TDP1 | |
| SCHEMBL24838097 | 0.80 | SMPD1 (0.47) | SMPD1ALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL19600796 | 0.79 | PPARA (0.44) | ALDH1A1TSHRTP53SMN1; SMN2TDP1 | |
| SCHEMBL25603628 | 0.79 | PPARA (0.52) | ALDH1A1TSHRSMN1; SMN2TDP1MAPK1 | |
| SCHEMBL10194129 | 0.77 | SMPD1 (0.51) | SMPD1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4751904 | 0.77 | VHL (0.54) | ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL14228524 | 0.77 | SMPD1 (0.47) | SMPD1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19598756 | 0.75 | PPARA (0.45) | ALDH1A1TSHRSMN1; SMN2TDP1PPARA | |
| SCHEMBL16705452 | 0.75 | SMN1; SMN2 (0.42) | ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230173078-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230173078-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCA2, SMARCC2 | SMPD1 1813/4885ALDH1A1 2230/4885TSHR 4388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.