Artemisin

Artemisin

SCHEMBL19600819

CC1CCC2[C@@H](C)C(=O)O[C@@H]3O[C@]4(C)CCC1[C@@]23OO4

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGES2 Q9H7Z7 9/20 1.00
ALDH1A1 P00352 4/20 1.00
LMNA P02545 3/20 1.00
HTT P42858 3/20 1.00
CYP1A2 P05177 2/20 1.00
CYP3A4 P08684 2/20 1.00
CYP2D6 P10635 1/20 1.00
CYP2C19 P33261 1/20 1.00
HIF1A Q16665 1/20 1.00
NR1I2 O75469 1/20 1.00
CYP2B6 P20813 1/20 1.00
GAA P10253 1/20 1.00
HPGD P15428 1/20 1.00
HSD17B10 Q99714 1/20 1.00
TP53 P04637 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Artemisinin SCHEMBL60304 1.00 PTGES2 (1.00) PTGES2ALDH1A1LMNAHTTCYP1A2
Artemisin SCHEMBL11959711 1.00 PTGES2 (1.00) PTGES2ALDH1A1LMNAHTTCYP1A2
Artemisin SCHEMBL7071338 1.00 PTGES2 (1.00) PTGES2ALDH1A1LMNAHTTCYP1A2
Artemisin SCHEMBL23843508 1.00 PTGES2 (1.00) PTGES2ALDH1A1LMNAHTTCYP1A2
Artemisin SCHEMBL13428542 1.00 PTGES2 (1.00) PTGES2ALDH1A1LMNAHTTCYP1A2
Artemisin SCHEMBL23974927 1.00 PTGES2 (1.00) PTGES2ALDH1A1LMNAHTTCYP1A2
Artemisin SCHEMBL16587860 1.00 PTGES2 (1.00) PTGES2ALDH1A1LMNAHTTCYP1A2
Artemisin SCHEMBL16587369 1.00 PTGES2 (1.00) PTGES2ALDH1A1LMNAHTTCYP1A2
Artemisin SCHEMBL9884398 1.00 PTGES2 (1.00) PTGES2ALDH1A1LMNAHTTCYP1A2
Artemisin SCHEMBL15372566 1.00 PTGES2 (1.00) PTGES2ALDH1A1LMNAHTTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170326102-A1 Pharmaceutical Composition Comprising an Artemisinin Derivative for Nasal or Pulmonary Delivery CIPLA LIMITED (IN) 2017-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170326102-A1 Pharmaceutical Composition Comprising an Artemisinin Derivative for Nasal or Pulmonary Delivery DIAPH1, DHPS, SQLE PTGES2 414/4885ALDH1A1 1769/4885LMNA 2017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.