SCHEMBL19601244

SCHEMBL19601244

C=C(C(C)c1ccc(CC(CC)(C(=O)c2ccc(F)cc2)N(C)C)cc1)N1CC(C)N(C(=O)C(C)c2ccc(CC(CC)(C(=O)c3ccc(F)cc3)N(C)C)cc2)CC1OC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MLNR O43193 1/20 0.31
CYP3A4 P08684 1/20 0.31
KCNH2 Q12809 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19601366 0.89 MLNR (0.36) MLNRCYP3A4KCNH2
SCHEMBL19601240 0.88 MAPKAPK2 (0.31)
SCHEMBL19601232 0.77 MLNR (0.42) MLNRCYP3A4
SCHEMBL19601247 0.76 MAPKAPK2 (0.35)
SCHEMBL17269438 0.74 PTGS2 (0.42)
SCHEMBL23152946 0.73 TSHR (0.52) MLNRCYP3A4
SCHEMBL17269443 0.73 MLNR (0.39) MLNRCYP3A4
SCHEMBL20988127 0.72 MLNR (0.38) MLNRCYP3A4
SCHEMBL2704437 0.71 RIPK1 (0.46)
SCHEMBL19601161 0.68 POLB (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017195428-A1 NOVEL COMPOUND, PHOTOCURABLE COMPOSITION, CURED PRODUCT THEREOF, PRINTING INK, AND PRINTED MATTER USING PRINTING INK DIC株式会社 2017-11-16 WO disclosed