Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14831525 | 1.00 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| SCHEMBL21388651 | 1.00 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| Hydrochloric Acid SCHEMBL21378503 | 0.98 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| Hydrochloric Acid SCHEMBL21378501 | 0.98 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| SCHEMBL847809 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| SCHEMBL18118180 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| SCHEMBL21388631 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| SCHEMBL8804245 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| SCHEMBL18012415 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EALOX15L3MBTL1 | |
| SCHEMBL21388627 | 0.84 | MAPT (0.60) | ALDH1A1MAPTKDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197036-A1 | SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2017-11-16 | — | — | WO | disclosed |