Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1239116 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4ENPSR1L3MBTL1 | |
| SCHEMBL19601809 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4ENPSR1L3MBTL1 | |
| SCHEMBL21388651 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4ENPSR1L3MBTL1 | |
| SCHEMBL14831525 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4ENPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL21378501 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ENPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL21378503 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ENPSR1L3MBTL1 | |
| SCHEMBL10404832 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4ENPSR1L3MBTL1 | |
| SCHEMBL277165 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4ENPSR1L3MBTL1 | |
| SCHEMBL847809 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ENPSR1L3MBTL1 | |
| SCHEMBL18118180 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ENPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |