SCHEMBL1960342

SCHEMBL1960342

CCCCCCCCCCCC(=O)N(CCO)CCNCC(=O)O.[NaH]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 4/20 0.46
PHF8 Q9UPP1 3/20 0.46
KDM4C Q9H3R0 3/20 0.46
EPHX2 P34913 2/20 0.44
KDM5C P41229 1/20 0.43
KDM5B Q9UGL1 1/20 0.43
GPR84 Q9NQS5 7/20 0.43
PPARG P37231 7/20 0.43
PPARD Q03181 7/20 0.43
PPARA Q07869 7/20 0.43
HDAC11 Q96DB2 5/20 0.43
TSHR P16473 4/20 0.43
PTPN1 P18031 3/20 0.43
ALDH1A1 P00352 2/20 0.43
TLR2 O60603 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
FABP4 P15090 2/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
SLC22A8 Q8TCC7 1/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5806921 0.99 KDM5A (0.47) KDM5APHF8KDM4CEPHX2KDM5C
SCHEMBL5807681 0.99 KDM5A (0.47) KDM5APHF8KDM4CEPHX2KDM5C
SCHEMBL1914762 0.99 KDM5A (0.47) KDM5APHF8KDM4CEPHX2KDM5C
SCHEMBL15842272 0.97 KDM5A (0.46) KDM5APHF8KDM4CEPHX2KDM5C
SCHEMBL30604057 0.97 KDM5A (0.46) KDM5APHF8KDM4CEPHX2KDM5C
SCHEMBL20786762 0.94 EPHX2 (0.54) EPHX2PPARGPPARDPPARAPTPN1
SCHEMBL13505363 0.92 EPHX2 (0.55) EPHX2PPARGPPARDPPARAPTPN1
SCHEMBL13505366 0.92 EPHX2 (0.55) EPHX2PPARGPPARDPPARAPTPN1
SCHEMBL14937709 0.92 KDM5A (0.46) KDM5APHF8KDM4CKDM5CKDM5B
SCHEMBL1960221 0.91 EPHX2 (0.54) EPHX2PPARGPPARDPPARAPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078211-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE DOW TORAY CO LTD (JP) 2026-03-19 US disclosed
EP-3368592-B1 COSMETIC COMPOSITION, COSMETIC, AND EXTERNAL PREPARATION FOR SKIN DOW TORAY CO LTD (JP) 2025-12-03 EP disclosed
EP-4626941-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE Dow Toray Co., Ltd. (JP) 2025-10-08 EP disclosed
US-12037467-B2 Oil-in-water-type emulsion composition, method for producing same, and use of same DOW TORAY CO., LTD. (JP) 2024-07-16 US disclosed
WO-2024113195-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESSTHEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE DOW TORAY CO., LTD. (JP) 2024-06-06 WO disclosed
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof DOW SILICONES CORPORATION (US) 2023-11-21 US disclosed
EP-2492301-B1 NOVEL CO-MODIFIED ORGANOPOLYSILOXANE DOW TORAY CO LTD (JP) 2023-03-29 EP disclosed
US-20220213309-A1 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION, COSMETIC INGREDIENT, COATING FORMING AGENT, AND COSMETIC CONTAINING SAME DOW TORAY CO., LTD. (JP) 2022-07-07 US disclosed
US-20220112322-A1 COMPOSITION, METHOD OF PREPARING COPOLYMER, AND METHODS AND END USES THEREOF DOW TORAY CO., LTD. (JP) 2022-04-14 US disclosed
EP-3950727-A1 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION, COSMETIC INGREDIENT, COATING FORMING AGENT, AND COSMETIC CONTAINING SAME Dow Toray Co., Ltd. (JP) 2022-02-09 EP disclosed
US-8147854-B2 Cosmetics comprising a modified organopolysiloxane DOW CORNING TORAY COMPANY, LTD. (JP) 2012-04-03 US disclosed
WO-2011136389-A2 COSMETIC AND TOPICAL SKIN PREPARATION COMPRISING HIGHER ALCOHOL-MODIFIED SILICONE DOW CORNING TORAY CO., LTD. (JP) 2011-11-03 WO disclosed
US-8034891-B2 Polyether-modified organopolysiloxane, diorganopolysiloxane-polyether block copolymer, their production methods, and cosmetic preparation DOW CORNING TORAY COMPANY, LTD. (JP) 2011-10-11 US disclosed
WO-2011078395-A2 THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT DOW CORNING TORAY CO., LTD. (JP) 2011-06-30 WO disclosed
WO-2011068251-A1 PRODUCTION METHOD OF DEODORIZED POLYOXYALKYLENE-MODIFIED POLYSILOXANE COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2011-06-09 WO disclosed
US-20100036062-A1 Polyether-Modified Organopolysiloxane, Diorganopolysiloxane-Polyether Block Copolymer, Their Production Methods, and Cosmetic Preparation DOW TORAY CO., LTD. (JP) 2010-02-11 US disclosed
US-20100028391-A1 Cosmetics Comprising A Modified Organopolysiloxane DOW CORNING TORAY COMPANY, LTD. (JP) 2010-02-04 US disclosed
EP-2022812-A1 POLYETHER-MODIFIED ORGANOPOLYSILOXANE, DIORGANOPOLYSILOXANE-POLYETHER BLOCK COPOLYMER, THEIR PRODUCTION METHODS, AND COSMETIC PREPARATION Dow Corning Toray Co., Ltd. (JP) 2009-02-11 EP disclosed
EP-1895979-A1 COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE Dow Corning Toray Co., Ltd. (JP) 2008-03-12 EP disclosed
WO-2006137576-A1 COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2006-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100028391-A1 Cosmetics Comprising A Modified Organopolysiloxane H1-0, H1-2, CHRM1 KDM5A 1484/4885PHF8 851/4885KDM4C 2073/4885
US-20260078211-A1 A SOLID PARTICLE OF ORGANOSILICON-FUNCTIONAL CO-POLYMER, MANUFACTURING PROCESS THEREOF, AND COSMETICS COMPRISING SAID SOLID PARTICLE FOXM1, FOXK1, TAF1L KDM5A 2720/4885PHF8 1960/4885KDM4C 3332/4885
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof BRS3, OXSR1, OXER1 KDM5A 4430/4885PHF8 3229/4885KDM4C 4318/4885
US-20220213309-A1 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION, COSMETIC INGREDIENT, COATING FORMING AGENT, AND COSMETIC CONTAINING SAME ADCY1, ADORA1, ADCY8 KDM5A 1478/4885PHF8 1138/4885KDM4C 3148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.