SCHEMBL1960366

SCHEMBL1960366

CCOC(=O)Oc1ccccc1-c1ccccc1OC(=O)OCC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.51
ELANE P08246 2/20 0.48
TSHR P16473 1/20 0.47
ALDH1A1 P00352 4/20 0.44
IDO1 P14902 1/20 0.44
TDO2 P48775 1/20 0.44
GLA P06280 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 1/20 0.41
PLIN1 O60240 1/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
PLIN5 Q00G26 1/20 0.41
KMT2A Q03164 1/20 0.41
ABHD5 Q8WTS1 1/20 0.41
SOAT1 P35610 1/20 0.41
PTPN1 P18031 1/20 0.41
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19320325 0.93 HPGD (0.51) TYMSELANETSHRALDH1A1IDO1
SCHEMBL16236877 0.93 TYMS (0.50) TYMSELANETSHRALDH1A1LMNA
SCHEMBL17698892 0.93 GLA (0.52) TYMSELANETSHRALDH1A1GLA
SCHEMBL17698885 0.92 CA1 (0.46) TYMSELANETSHRALDH1A1IDO1
Hydrochloric Acid SCHEMBL16236992 0.90 TYMS (0.45) TYMSELANETSHRALDH1A1IDO1
Hydrochloric Acid SCHEMBL16236993 0.90 TYMS (0.45) TYMSELANETSHRALDH1A1IDO1
SCHEMBL8516383 0.90 TSHR (0.52) TYMSELANETSHRALDH1A1GLA
SCHEMBL1839147 0.90 L3MBTL1 (0.49) TYMSALDH1A1L3MBTL1LMNA
SCHEMBL16236731 0.89 ELANE (0.51) TYMSELANETSHRGLALMNA
SCHEMBL16236566 0.87 HSD17B10 (0.57) TYMSELANETSHRL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170256819-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND ENERGY STORAGE DEVICE USING SAME UBE INDUSTRIES, LTD. (JP) 2017-09-07 US claimed
EP-2507269-B1 THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE GRACE W R & CO (US) 2014-10-29 EP claimed
US-8633126-B2 Three and four atom bridged dicarbonate compounds as internal donors in catalysts for polypropylene manufacture DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-21 US claimed
EP-2507269-A1 THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE Dow Global Technologies LLC (US) 2012-10-10 EP claimed
WO-2011068775-A1 THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE DOW GLOBAL TECHNOLOGIES INC. (US) 2011-06-09 WO claimed
US-20110130529-A1 THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE DOW GLOBAL TECHNOLOGIES INC. (US) 2011-06-02 US claimed
US-20170256819-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND ENERGY STORAGE DEVICE USING SAME UBE INDUSTRIES, LTD. (JP) 2017-09-07 US disclosed
US-20170256819-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND ENERGY STORAGE DEVICE USING SAME UBE INDUSTRIES, LTD. (JP) 2017-09-07 US disclosed
US-20170256819-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND ENERGY STORAGE DEVICE USING SAME UBE INDUSTRIES, LTD. (JP) 2017-09-07 US disclosed
EP-2507269-B1 THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE GRACE W R & CO (US) 2014-10-29 EP disclosed
EP-2507269-B1 THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE GRACE W R & CO (US) 2014-10-29 EP disclosed
US-8633126-B2 Three and four atom bridged dicarbonate compounds as internal donors in catalysts for polypropylene manufacture DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-21 US disclosed
US-8633126-B2 Three and four atom bridged dicarbonate compounds as internal donors in catalysts for polypropylene manufacture DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-21 US disclosed
US-8633126-B2 Three and four atom bridged dicarbonate compounds as internal donors in catalysts for polypropylene manufacture DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-21 US disclosed
EP-2507269-A1 THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE Dow Global Technologies LLC (US) 2012-10-10 EP disclosed
WO-2011068775-A1 THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE DOW GLOBAL TECHNOLOGIES INC. (US) 2011-06-09 WO disclosed
WO-2011068775-A1 THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE DOW GLOBAL TECHNOLOGIES INC. (US) 2011-06-09 WO disclosed
US-20110130529-A1 THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE DOW GLOBAL TECHNOLOGIES INC. (US) 2011-06-02 US disclosed
US-20110130529-A1 THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE DOW GLOBAL TECHNOLOGIES INC. (US) 2011-06-02 US disclosed
US-20110130529-A1 THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE DOW GLOBAL TECHNOLOGIES INC. (US) 2011-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130529-A1 THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE XRN2, RAD52, TELO2 TYMS 1615/4885ELANE 3376/4885TSHR 2341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.