XRN2

5'-3' exoribonuclease 2 · Q9H0D6 · XRN2 on Sugi Atlas →

0 patent compounds predicted against XRN2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to XRN2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
S0720: Adjuvant Therapy Based on Gene Expression in Stage IA and IB Non-Small Cell Lung Cancer PHASE2COMPLETED
Veliparib With or Without Radiation Therapy, Carboplatin, and Paclitaxel in Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery PHASE1/PHASE2ACTIVE_NOT_RECRUITING
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma PHASE1/PHASE2COMPLETED
Selinexor With ICE Chemotherapy in Secondary Central Nervous System Involving B-cell Non-Hodgkin Lymphoma PHASE1/PHASE2RECRUITING
A Phase I Trial of SHR3162 in Subjects With Advanced Solid Tumors PHASE1COMPLETED
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing nanRECRUITING
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Spironolactone and XPB-1 Integrity in the TFIIH Complex nanENROLLING_BY_INVITATION
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma(SELINA) nanRECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Diagnosis and Phenotype Characterisation Using Genomics in Patients With Inherited Bone Marrow Failure (IBMDx Study) nanRECRUITING
B3 for NMD: Bench to Bedside and Back nanENROLLING_BY_INVITATION
Biocollection in MyeloDysplastic Syndrome (P-MDS) nanRECRUITING
Diagnosis of Inflammatory Bowel Disease nanNOT_YET_RECRUITING
A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients nanCOMPLETED
DNA Repair Genes and Outcomes in Patients With Stage III NSCLC nanUNKNOWN
Study of Specimens From Young Patients With Neuroblastoma nanCOMPLETED
DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery Disease nanCOMPLETED
Mutations and Phenotypes of Unclassifiable Inherited Bone Marrow Failure Syndromes nanRECRUITING
Thoracic Aortic Dilatation Syndromes nanCOMPLETED
Precision Genomics Medicine Biobank nanRECRUITING
Study of Constitutional Platelet Disease nanUNKNOWN
Immunohistochemical Expression of Excision Repair Cross Complementation Group 1 (ERCC1) in Laryngeal Squamous Cell Carcinoma and Its Correlation With Response to Radiotherapy. nanUNKNOWN
Endolymphatic Sac Tumors in a Population of Patients With Von Hippel-Lindau Disease:The Natural History and Pathobiology, and a Prospective Non-Randomized Clinical Trial of Hearing Preservation Surgery in Patients With Early Stage Endolymphatic Sac Tumors nanCOMPLETED
Biomarkers in Patients With Diffuse Large B-Cell Lymphoma Treated With Combination Chemotherapy With or Without Rituximab nanCOMPLETED
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a XRN2 binder may also engage these)

ProteinNameSimilarity
Q9DBR1 1.000 Q9DBR1 →
Q5R4L5 1.000 Q5R4L5 →
Q5ZIP4 1.000 Q5ZIP4 →
Q8TFZ1 1.000 Q8TFZ1 →
Q9FQ03 1.000 Q9FQ03 →
Q5BFH3 0.999 Q5BFH3 →
Q9FQ04 0.999 Q9FQ04 →
Q4HWE2 0.998 Q4HWE2 →
Q74ZA0 0.997 Q74ZA0 →
P40848 0.996 P40848 →
Q6BNU7 0.995 Q6BNU7 →
Q02792 0.995 Q02792 →
Q6FKN6 0.995 Q6FKN6 →
Q6CKX0 0.995 Q6CKX0 →
Q9U299 0.995 Q9U299 →
Q2GNZ6 0.995 Q2GNZ6 →
Q2UCP5 0.994 Q2UCP5 →
Q60SG7 0.994 Q60SG7 →
Q5AMG5 0.993 Q5AMG5 →
P0CL88 0.993 P0CL88 →
P0CL89 0.992 P0CL89 →
Q9VM71 0.992 Q9VM71 →
Q6C961 0.991 Q6C961 →
Q8WZX5 0.991 Q8WZX5 →
Q4P149 0.991 Q4P149 →
Q9NAA5 0.989 Q9NAA5 →
DHX29 ATP-dependent RNA helicase DHX29 0.988 landscape →
Q14562 0.988 Q14562 →
O35066 0.987 O35066 →
A8XYX2 0.987 A8XYX2 →