Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 10/20 | 0.38 |
| ▸ | MAOA | P21397 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19604352 | 0.81 | MAPT (0.47) | ALDH1A1MAPTHPGDGAATSHR | |
| SCHEMBL8830144 | 0.76 | ALDH1A1 (0.42) | MAOBMAOAALDH1A1MAPTHPGD | |
| SCHEMBL5913725 | 0.76 | CYP4F2 (0.41) | MAOBMAOAALDH1A1MAPTHPGD | |
| SCHEMBL19240330 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPTGAAKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL5913379 | 0.73 | MAOB (0.38) | MAOBMAOAALDH1A1MAPTHPGD | |
| SCHEMBL19251029 | 0.73 | NPC1 (0.37) | MAOBMAOAALDH1A1GAAHSD17B10 | |
| SCHEMBL5913429 | 0.72 | NOS1 (0.41) | ALDH1A1GAATSHR | |
| SCHEMBL14081877 | 0.72 | ALDH1A1 (0.36) | ESRRBESRRGMAOBMAOAALDH1A1 | |
| SCHEMBL17740144 | 0.72 | ALDH1A1 (0.42) | MAOBMAOAALDH1A1MAPTHPGD | |
| SCHEMBL19251337 | 0.71 | MAOB (0.53) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170326250-A1 | CELL PROLIFERATION INHIBITORS AND CONJUGATES THEREOF | NOVARTIS AG (CH) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170326250-A1 | CELL PROLIFERATION INHIBITORS AND CONJUGATES THEREOF | MKI67, CCNI, PA2G4 | ESRRB 3275/4885ESRRG 3143/4885MAOB 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.