Dipyridyl

Dipyridyl

SCHEMBL1960478

[Os].c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.93
LMNA P02545 3/20 0.93
CCR1 P32246 3/20 0.93
CCR5 P51681 3/20 0.93
CCR8 P51685 3/20 0.93
CYP1A2 P05177 1/20 0.93
POLB P06746 1/20 0.93
METAP1 P53582 1/20 0.93
BLM P54132 1/20 0.93
HIF1A Q16665 1/20 0.93
DOHH Q9BU89 1/20 0.93
P4HTM Q9NXG6 1/20 0.93
NPC1 O15118 6/20 0.74
TP53 P04637 4/20 0.74
RAB9A P51151 4/20 0.74
ALOX15 P16050 3/20 0.74
SMN1; SMN2 Q16637 3/20 0.74
L3MBTL1 Q9Y468 3/20 0.74
HTT P42858 2/20 0.74
TDP1 Q9NUW8 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL143849 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29601520 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL1699769 1.00 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL6036064 0.97 KDM4E (0.88) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL5922 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29351528 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29907716 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL3711450 0.97 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL8655605 0.93 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL15136892 0.93 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3781701-B1 DETECTION OF BACTERIA ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2022-06-01 EP claimed
EP-3781701-A1 DETECTION OF BACTERIA Ecole Polytechnique Federale de Lausanne (EPFL) (CH) 2021-02-24 EP claimed
WO-2019201986-A1 DETECTION OF BACTERIA ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2019-10-24 WO claimed
US-8865890-B2 Redox-active structures and devices utilizing the same YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2014-10-21 US claimed
US-20140196180-A1 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME YEDA RESEARCH & DEVELOPMENT COMPANY LTD. (IL) 2014-07-10 US claimed
WO-2013023671-A1 MICROFLUIDIC DEVICE AND METHOD FOR DETECTING ANALYTES IN A FLOW USING ELECTROCHEMICAL PROBES DA MOTA NICOLAS (FR) 2013-02-21 WO claimed
US-20100304357-A1 UNIVERSAL DRINKING ADAPTER FOR BEVERAGE BOTTLES, AND DEVICES AND KITS FOR DETERMINING SMALL MOLECULES, METAL IONS, ENDOTOXINS, AND BACTERIA, AND METHODS OF USE THEREOF SUREMILK, LLC 2010-12-02 US claimed
EP-2205497-A1 UNIVERSAL DRINKING ADAPTER FOR BEVERAGE BOTTLES TO ALLOW FOR LIQUID CONSUMPTION AND DEVICES AND KITS FOR DETERMINING SMALL MOLECULES, METAL IONS, ENDOTOXINS, AND BACTERIA FOUND IN MILK, AND METHODS OF USE THEREOF Suremilk, LLC. (US) 2010-07-14 EP claimed
WO-2009033135-A1 UNIVERSAL DRINKING ADAPTER FOR BEVERAGE BOTTLES TO ALLOW FOR LIQUID CONSUMPTION AND DEVICES AND KITS FOR DETERMINING SMALL MOLECULES, METAL IONS, ENDOTOXINS, AND BACTERIA FOUND IN MILK, AND METHODS OF USE THEREOF SUREMILK, LLC. (US) 2009-03-12 WO claimed
US-20080057559-A1 Rate measurements of biomolecular reactions using electrochemiluminescence BIOVERIS CORPORATION 2008-03-06 US claimed
US-20070258147-A1 Redox-active structures and devices utilizing the same YEDA RESEARCH & DEVELOPMENT CO., LTD. (IL) 2007-11-08 US claimed
EP-0871891-B1 RATE MEASUREMENTS OF BIOMOLECULAR REACTIONS USING ELECTROCHEMILUMINESCENCE BIOVERIS CORP (US) 2006-03-08 EP claimed
US-20020051893-A1 High brightness and low voltage operated LEDs based on inorganic salts as emitters and conductive materials as cathodic contacts BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2002-05-02 US claimed
WO-2001093346-A2 HIGH BRIGHTNESS AND LOW VOLTAGE OPERATED LEDS BASED ON INORGANIC SALTS AS EMITTERS AND CONDUCTIVE MATERIALS AS CATHODIC CONTACTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2001-12-06 WO claimed
EP-0871891-A4 RATE MEASUREMENTS OF BIOMOLECULAR REACTIONS USING ELECTROCHEMILUMINESCENCE IGEN INC (US) 1998-12-30 EP claimed
EP-0871891-A1 RATE MEASUREMENTS OF BIOMOLECULAR REACTIONS USING ELECTROCHEMILUMINESCENCE IGEN, INC. (US) 1998-10-21 EP claimed
WO-1996017248-A9 RATE MEASUREMENTS OF BIOMOLECULAR REACTIONS USING ELECTROCHEMILUMINESCENCE 1996-11-07 WO claimed
US-5527710-A MIXING REACTANT, LUMINOPHORE, BIOMOLECULAR REACTION PARTNER, EXPOSING TO SERIES OF ELECTRICAL PULSES AT PRESELECTED POTENTIAL AND INTERVALS, MEASURING ELECTROCHEMILUMINESCENCE, REPEATING WITH REACTED MIXTURE, AND WITHOUT REACTION PARTNER IGEN, INC. (US) 1996-06-18 US claimed
WO-1996017248-A1 RATE MEASUREMENTS OF BIOMOLECULAR REACTIONS USING ELECTROCHEMILUMINESCENCE IGEN, INC. (US) 1996-06-06 WO claimed
US-4381978-A Photoelectrochemical system and a method of using the same ENGELHARD CORPORATION (US) 1983-05-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140196180-A1 REDOX-ACTIVE STRUCTURES AND DEVICES UTILIZING THE SAME GPX4, GPX1, LPO KDM4E 2794/4885LMNA 1475/4885CCR1 4828/4885
US-20070258147-A1 Redox-active structures and devices utilizing the same GPX4, GPX1, LPO KDM4E 2794/4885LMNA 1475/4885CCR1 4828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.