Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 7/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 8/20 | 0.33 |
| ▸ | CA1 | P00915 | 7/20 | 0.33 |
| ▸ | CA2 | P00918 | 7/20 | 0.33 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA4 | P22748 | 4/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.32 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.30 |
| ▸ | CA6 | P23280 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA7 | P43166 | 2/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19605919 | 0.96 | CA9 (0.39) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL18281369 | 0.93 | CA9 (0.41) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL18281370 | 0.93 | CA9 (0.41) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL21117586 | 0.92 | CA9 (0.40) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL20515160 | 0.88 | CA9 (0.43) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL20515159 | 0.88 | CA9 (0.43) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL29410425 | 0.88 | CA9 (0.43) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL29410424 | 0.88 | CA9 (0.43) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL18291960 | 0.88 | CA9 (0.42) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL19605826 | 0.87 | CA9 (0.39) | CA9ALBDGAT1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197251-A1 | NUCLEAR IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-11-16 | — | — | WO | disclosed |