Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 8/20 | 0.34 |
| ▸ | CA1 | P00915 | 5/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.33 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18281369 | 0.97 | CA9 (0.41) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL18281370 | 0.97 | CA9 (0.41) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL19605828 | 0.96 | CA9 (0.38) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL21117586 | 0.95 | CA9 (0.40) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL18292015 | 0.90 | DGAT1 (0.37) | DGAT1FOLH1CHRNA7CHRNA10CHRNA9 | |
| SCHEMBL20515160 | 0.89 | CA9 (0.43) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL20515159 | 0.89 | CA9 (0.43) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL29410425 | 0.89 | CA9 (0.43) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL29410424 | 0.89 | CA9 (0.43) | CA9ALBDGAT1CA1CA2 | |
| SCHEMBL18291960 | 0.89 | CA9 (0.42) | CA9ALBDGAT1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197251-A1 | NUCLEAR IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-11-16 | — | — | WO | disclosed |