Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | G6PD | P11413 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19261768 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL29946422 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL2346534 | 0.79 | HSP90AA1 (0.46) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL3175174 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL10067848 | 0.78 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDNAPRTALOX15 | |
| SCHEMBL13081953 | 0.78 | ALB (0.57) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL3418836 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL20740635 | 0.77 | CYP1A2 (0.52) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL7691220 | 0.75 | SELL (0.59) | ALDH1A1KDM4EHPGDCA12CA1 | |
| SCHEMBL19005982 | 0.75 | SELL (0.65) | ALDH1A1KDM4EHPGDCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626141-B2 | Method for specific cleavage of C alpha-C bond and side chain of protein and peptide, and method for determining amino acid sequence | SHIMADZU CORPORATION (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20170327533-A1 | METHOD FOR SPECIFIC CLEAVAGE OF C Alpha-C BOND AND SIDE CHAIN OF PROTEIN AND PEPTIDE, AND METHOD FOR DETERMINING AMINO ACID SEQUENCE | SHIMADZU CORPORATION (JP) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327533-A1 | METHOD FOR SPECIFIC CLEAVAGE OF C Alpha-C BOND AND SIDE CHAIN OF PROTEIN AND PEPTIDE, AND METHOD FOR DETERMINING AMINO ACID SEQUENCE | CPN1, CYBA, CRYAB | ALDH1A1 3311/4885KDM4E 3346/4885HPGD 2172/4885 |
| US-10626141-B2 | Method for specific cleavage of C alpha-C bond and side chain of protein and peptide, and method for determining amino acid sequence | CPN1, CYBA, CRYAB | ALDH1A1 3311/4885KDM4E 3346/4885HPGD 2172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.