⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19585689 | 0.66 | MAP3K14 (0.33) | — | |
| SCHEMBL20206747 | 0.59 | CRBN (0.33) | — | |
| SCHEMBL3650532 | 0.50 | — | — | |
| SCHEMBL48364 | 0.50 | — | — | |
| SCHEMBL168361 | 0.50 | — | — | |
| SCHEMBL11835120 | 0.49 | MAP3K14 (0.43) | — | |
| SCHEMBL11645491 | 0.49 | MAP3K14 (0.48) | — | |
| Hydrochloric Acid SCHEMBL17873779 | 0.49 | — | — | |
| Hydrochloric Acid SCHEMBL19359380 | 0.49 | — | — | |
| Hydrochloric Acid SCHEMBL19359427 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197051-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2017-11-16 | — | — | WO | disclosed |