⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31738380 | 0.75 | NOS1 (0.37) | — | |
| SCHEMBL1958525 | 0.73 | — | — | |
| SCHEMBL19285570 | 0.68 | — | — | |
| SCHEMBL2579553 | 0.66 | TSHR (0.41) | — | |
| SCHEMBL12574781 | 0.64 | CYP1A1 (0.34) | — | |
| SCHEMBL13900590 | 0.64 | — | — | |
| SCHEMBL37337 | 0.64 | — | — | |
| SCHEMBL19139531 | 0.64 | — | — | |
| SCHEMBL7096785 | 0.63 | — | — | |
| SCHEMBL11231100 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065756-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130065756-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130065756-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
| EP-2507213-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | Syngenta Participations AG (CH) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011067131-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011067131-A1 | SPIROHETEROCYCLIC DIONE DERIVATIVES USED AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-09 | — | — | WO | disclosed |