⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561822 | 0.84 | — | — | |
| SCHEMBL9059532 | 0.74 | — | — | |
| SCHEMBL13900590 | 0.72 | — | — | |
| SCHEMBL6766633 | 0.72 | — | — | |
| SCHEMBL248989 | 0.72 | — | — | |
| SCHEMBL11231100 | 0.71 | — | — | |
| SCHEMBL7096785 | 0.71 | — | — | |
| SCHEMBL612354 | 0.70 | L3MBTL1 (0.44) | — | |
| SCHEMBL22283801 | 0.70 | GLA (0.32) | — | |
| SCHEMBL22283804 | 0.70 | KMT2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4596544-A1 | EP300/CBP REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Miracure Biotechnology Limited (CN) | 2025-08-06 | — | — | EP | disclosed |
| WO-2025036453-A1 | EGFR MUTATION INHIBITORS AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2025-02-20 | — | — | WO | disclosed |
| US-11980188-B2 | Spiro cyclohexanedione derivates as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2024-05-14 | — | — | US | disclosed |
| CN-117843618-A | EP300/CBP regulator and preparation method and application thereof | 北京沐华生物科技有限责任公司 | 2024-04-09 | — | — | CN | disclosed |
| US-20240109868-A1 | EP300/CBP MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Miracure Biotechnology Limited (CN) | 2024-04-04 | — | — | US | disclosed |
| WO-2024046504-A1 | EP300/CBP REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 北京沐华生物科技有限责任公司 | 2024-03-07 | — | — | WO | disclosed |
| CN-111868034-B | Spirocyclic cyclohexanedione derivatives as herbicides | 先正达参股股份有限公司 | 2023-12-01 | — | — | CN | disclosed |
| WO-2023189433-A1 | ULTRAVIOLET RADIATION-CURABLE POLYSILOXANE COMPOSITION, AND DAMPING MATERIAL | 株式会社タイカ | 2023-10-05 | — | — | WO | disclosed |
| EP-3765445-B1 | SPIRO CYCLOHEXANEDIONE DERIVATES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-08-30 | — | — | EP | disclosed |
| EP-3765445-A1 | SPIRO CYCLOHEXANEDIONE DERIVATES AS HERBICIDES | Syngenta Participations AG (CH) | 2021-01-20 | — | — | EP | disclosed |
| WO-2010066780-A1 | SPIROHETEROCYCLIC N-OXYPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-17 | — | — | WO | disclosed |
| WO-2010063670-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-10 | — | — | WO | disclosed |
| US-20090156574-A1 | 2-ACYLAMINO-4-PHENYLTHIAZOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2009-06-18 | — | — | US | disclosed |
| WO-2009049851-A1 | SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| US-7504511-B2 | 2-acylamino-4-phenylthiazole derivatives, preparation thereof and therapeutic application thereof | SANOFI-AVENTIS (FR) | 2009-03-17 | — | — | US | disclosed |
| CN-1098259-C | Novel carboxy-substituted cyclic carboxamide derivatives | AVENTIS PHARMA INC (US) | 2003-01-08 | — | — | CN | disclosed |
| CN-1240443-A | Novel carboxy substituted cyclic carboxamide derivatives | HOECHST MARION ROUSSEL INC (US) | 2000-01-05 | — | — | CN | disclosed |
| EP-0699195-A1 | THIOINDOLE PYPERIDINYL DERIVATIVES USED AS ANTALGICS | LABORATOIRES UPSA (FR) | 1996-03-06 | — | — | EP | disclosed |
| US-5418242-A | Piperidinylthioindole derivatives, their methods of preparation and pharmaceutical compositions in which they are present, useful especially as analgesics | LABORATOIRES UPSA (FR) | 1995-05-23 | — | — | US | disclosed |
| WO-1994026736-A1 | THIOINDOLE PYPERIDINYL DERIVATIVES USED AS ANTALGICS | LABORATOIRES UPSA (FR) | 1994-11-24 | — | — | WO | disclosed |