SCHEMBL19607015

SCHEMBL19607015

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3cc(-c4cccc5c4oc4ccccc45)cc4c3oc3ccccc34)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.50
GGPS1 O95749 1/20 0.41
PRKDC P78527 7/20 0.38
PTGES2 Q9H7Z7 1/20 0.38
PLA2G2A P14555 3/20 0.36
PLA2G4A P47712 3/20 0.36
AHR P35869 1/20 0.35
PLA2G10 O15496 1/20 0.34
ATM Q13315 1/20 0.34
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
PIM1 P11309 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
TNKS O95271 1/20 0.33
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32
CDC14B O60729 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25550474 0.94 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL24782069 0.92 ALOX5 (0.45) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL25550479 0.90 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL29312226 0.90 PLA2G2A (0.40) ALOX5PLA2G2APLA2G4AAHRPLA2G10
SCHEMBL29312239 0.90 PLA2G2A (0.40) ALOX5PLA2G2APLA2G4AAHRPLA2G10
SCHEMBL19606982 0.90 PLA2G2A (0.40) ALOX5PLA2G2APLA2G4AAHRPLA2G10
SCHEMBL29312197 0.90 PLA2G2A (0.40) ALOX5PLA2G2APLA2G4AAHRPLA2G10
SCHEMBL27050379 0.89 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL26355884 0.89 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL19607071 0.89 ALOX5 (0.51) ALOX5GGPS1PRKDCPTGES2PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017196081-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SK CHEMICALS CO., LTD. (KR) 2017-11-16 WO disclosed