Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CTSD | P07339 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19607356 | 0.88 | EPHX1 (0.46) | CTSKEPHX1ALDH1A1MEN1TSHR | |
| SCHEMBL19607358 | 0.85 | CTSL (0.47) | CTSLCTSBCTSDCTSSUSP2 | |
| SCHEMBL12524368 | 0.78 | EPHX1 (0.40) | CTSLCTSBCTSDCTSSEPHX1 | |
| SCHEMBL17028383 | 0.75 | HTT (0.55) | CTSLCTSBCTSDCTSSUSP2 | |
| SCHEMBL24951478 | 0.75 | EPHX1 (0.44) | CTSLCTSBCTSDCTSSEPHX1 | |
| SCHEMBL5619020 | 0.75 | EPHX1 (0.44) | EPHX1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL1328433 | 0.74 | CTSD (0.54) | CTSLCTSBCTSDCTSSUSP2 | |
| SCHEMBL20806059 | 0.72 | TDP1 (0.46) | EPHX1MEN1KMT2AHTT | |
| SCHEMBL1495989 | 0.72 | EPHX1 (0.49) | EPHX1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL13055387 | 0.72 | EPHX1 (0.53) | CTSSCTSKEPHX1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017197324-A1 | ADRENERGIC RECEPTOR MODULATING COMPOUNDS AND METHODS OF USING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-11-16 | — | — | WO | disclosed |