Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13411699 | 0.92 | KMT2A (0.52) | MEN1KMT2AEPHX2SMN1; SMN2GAA | |
| SCHEMBL19171879 | 0.89 | KMT2A (0.48) | MEN1KMT2AEPHX2SMN1; SMN2GAA | |
| SCHEMBL2632920 | 0.87 | — | — | |
| SCHEMBL6286871 | 0.86 | KMT2A (0.47) | MEN1KMT2AEPHX2SMN1; SMN2GAA | |
| SCHEMBL12339213 | 0.85 | MEN1 (0.43) | MEN1KMT2AEPHX2SMN1; SMN2GAA | |
| SCHEMBL26669195 | 0.84 | EPHX2 (0.51) | MEN1KMT2AEPHX2SMN1; SMN2KEAP1 | |
| SCHEMBL19593906 | 0.84 | KMT2A (0.46) | MEN1KMT2AEPHX2SMN1; SMN2KEAP1 | |
| SCHEMBL6290245 | 0.84 | MEN1 (0.46) | MEN1KMT2AEPHX2SMN1; SMN2TSHR | |
| SCHEMBL6290526 | 0.83 | KMT2A (0.44) | MEN1KMT2AEPHX2SMN1; SMN2GAA | |
| SCHEMBL14984056 | 0.82 | EPHX1 (0.47) | MEN1KMT2AEPHX2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111521-A1 | AROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 杭州多域生物技术有限公司 | 2022-06-02 | — | — | WO | disclosed |
| WO-2017195880-A1 | HYALURONIC ACID DERIVATIVE HAVING CATIONIC GROUP AND HYDROPHOBIC GROUP INTRODUCED THEREIN | 中外製薬株式会社 | 2017-11-16 | — | — | WO | disclosed |