SCHEMBL1960798

SCHEMBL1960798

COC(=O)C(COc1ccccc1)(Oc1ccccc1)C(=O)OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
RAB9A P51151 2/20 0.45
KCNN4 O15554 1/20 0.44
ALOX15 P16050 1/20 0.43
MTNR1A P48039 4/20 0.42
MTNR1B P49286 4/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
PPARG P37231 2/20 0.41
SRC P12931 1/20 0.41
SSTR4 P31391 1/20 0.40
ALPL P05186 1/20 0.40
ALPI P09923 1/20 0.40
ALPG P10696 1/20 0.40
RECQL P46063 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
MAPK10 P53779 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1964634 0.84 TDP1 (0.50) MAPTRAB9AALOX15MTNR1AMTNR1B
SCHEMBL36735 0.82 ALOX15 (0.48) ALOX15MTNR1AMTNR1BPPARGALPL
SCHEMBL5367643 0.79 SSTR4 (0.51) MAPTRAB9AKCNN4ALOX15MTNR1A
SCHEMBL11366536 0.79 PARP10 (0.46) MAPTALOX15PPARGRECQLALDH1A1
SCHEMBL4404312 0.77 MAPT (0.45) MAPTRAB9AKCNN4ALOX15MTNR1A
SCHEMBL7288524 0.73 KCNN4 (0.52) MAPTKCNN4L3MBTL1PPARGSRC
SCHEMBL11355320 0.72 KCNN4 (0.47) MAPTRAB9AKCNN4MTNR1AMTNR1B
SCHEMBL8816512 0.72 KCNN4 (0.50) MAPTRAB9AKCNN4SRCALDH1A1
SCHEMBL8468475 0.72 KCNN4 (0.50) MAPTRAB9AKCNN4L3MBTL1PPARG
SCHEMBL28644949 0.72 KCNN4 (0.50) MAPTRAB9AKCNN4L3MBTL1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120302722-A1 COPOLYETHER ESTER ELASTOMER INVISTA NORTH AMERICA S.A.R.L (US) 2012-11-29 US claimed
EP-2510039-A1 COPOLYETHER ESTER ELASTOMER Invista Technologies S.à.r.l. (CH) 2012-10-17 EP claimed
WO-2011071558-A1 COPOLYETHER ESTER ELASTOMER INVISTA TECHNOLOGIES S.A R.L. (CH) 2011-06-16 WO claimed
US-20120302722-A1 COPOLYETHER ESTER ELASTOMER INVISTA NORTH AMERICA S.A.R.L (US) 2012-11-29 US disclosed
EP-2510039-A1 COPOLYETHER ESTER ELASTOMER Invista Technologies S.à.r.l. (CH) 2012-10-17 EP disclosed
WO-2011071558-A1 COPOLYETHER ESTER ELASTOMER INVISTA TECHNOLOGIES S.A R.L. (CH) 2011-06-16 WO disclosed
US-6833428-B1 Polyetherester elastomer ASAHI KASEI KABUSHIKI KAISHA (JP) 2004-12-21 US disclosed