Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.43 |
| ▸ | MAP3K8 | P41279 | 9/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19610587 | 0.84 | MAP3K8 (0.43) | ACP1MAP3K8PTGS1PTGS2EGFR | |
| SCHEMBL19610564 | 0.84 | CHEK1 (0.40) | MAP3K8PTGS1PTGS2EGFRERBB2 | |
| SCHEMBL19610605 | 0.83 | KMT2A (0.41) | PTGS1PTGS2 | |
| SCHEMBL19610577 | 0.80 | SMN1; SMN2 (0.54) | EGFR | |
| SCHEMBL19610568 | 0.78 | TRPV1 (0.38) | ACP1RPS6KB1EGFRERBB2 | |
| SCHEMBL19610576 | 0.78 | MET (0.38) | — | |
| SCHEMBL19610519 | 0.77 | SRC (0.45) | — | |
| SCHEMBL6089017 | 0.76 | POLA1 (0.43) | ACP1PTK6AURKARPS6KB1ABCG2 | |
| SCHEMBL19610549 | 0.75 | AXL (0.44) | ACP1EGFR | |
| SCHEMBL6088154 | 0.74 | SLC2A1 (0.40) | ACP1PTK6AURKARPS6KB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198756-A1 | QUINOLINE COMPOUNDS FOR INCREASING INSULINE RELEASE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-11-23 | — | — | WO | claimed |
| EP-3246028-A1 | QUINOLINE COMPOUNDS FOR INCREASING INSULINE RELEASE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-11-22 | — | — | EP | claimed |
| WO-2017198756-A1 | QUINOLINE COMPOUNDS FOR INCREASING INSULINE RELEASE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-11-23 | — | — | WO | disclosed |
| EP-3246028-A1 | QUINOLINE COMPOUNDS FOR INCREASING INSULINE RELEASE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-11-22 | — | — | EP | disclosed |