Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 11/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 10/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 9/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19610999 | 0.88 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2L3MBTL1ALDH1A1 | |
| SCHEMBL19611046 | 0.84 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2ALDH1A1LMNA | |
| SCHEMBL19610988 | 0.81 | TAS1R3 (0.42) | TAS1R3TAS1R1TAS1R2CHRNA7HPGD | |
| SCHEMBL15506751 | 0.81 | DRD4 (0.65) | DRD4TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL19611049 | 0.79 | ALDH1A1 (0.44) | TAS1R3TAS1R1TAS1R2L3MBTL1ALDH1A1 | |
| SCHEMBL19611022 | 0.77 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2CHRNA7ALDH1A1 | |
| SCHEMBL19611026 | 0.76 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2HPGDL3MBTL1 | |
| SCHEMBL19611031 | 0.74 | TAS1R3 (0.52) | TAS1R3TAS1R1TAS1R2HPGDL3MBTL1 | |
| SCHEMBL19610986 | 0.74 | TAS1R3 (0.52) | TAS1R3TAS1R1TAS1R2HPGDL3MBTL1 | |
| SCHEMBL19611051 | 0.74 | TAS1R3 (0.52) | TAS1R3TAS1R1TAS1R2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892880-B1 | INDOLE CARBOXAMIDE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2017-11-22 | — | — | EP | claimed |