Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 4/20 | 0.50 |
| ▸ | LDHB | P07195 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5850910 | 0.85 | LDHA (0.54) | LDHALDHBPTPN1PTPN11FFAR1 | |
| SCHEMBL5588178 | 0.85 | LDHA (0.54) | LDHALDHBPTPN1PTPN11FFAR1 | |
| SCHEMBL28656372 | 0.81 | LDHA (0.50) | LDHALDHBPTPN1PTPN11FFAR1 | |
| SCHEMBL4122794 | 0.81 | LDHA (0.50) | LDHALDHBPTPN1PTPN11FFAR1 | |
| SCHEMBL5587507 | 0.80 | LDHA (0.50) | LDHALDHBPTPN1PTPN11FFAR1 | |
| SCHEMBL9040916 | 0.80 | LDHA (0.53) | LDHALDHBPTPN1PTPN11FFAR1 | |
| SCHEMBL14031682 | 0.78 | LDHA (0.46) | LDHALDHBPTPN1PTPN11JUN | |
| SCHEMBL15841763 | 0.78 | LDHA (0.59) | LDHALDHBPTPN1PTPN11FFAR1 | |
| SCHEMBL5589890 | 0.77 | LDHA (0.50) | LDHALDHBPTPN1PTPN11FFAR1 | |
| SCHEMBL5589034 | 0.76 | LDHA (0.57) | LDHALDHBPTPN1PTPN11FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847257-B1 | Solid preparation comprising enteric solid dispersion | SHINETSU CHEMICAL CO (JP) | 2017-11-22 | — | — | EP | claimed |