Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 2/20 | 0.32 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10875349 | 0.81 | CYP3A4 (0.41) | CYP3A4MAPK1CYP2A6AHRTDP1 | |
| SCHEMBL11177494 | 0.79 | CYP1A2 (0.32) | CYP2A6AHRTSHRCYP1A2HTR2A | |
| SCHEMBL1446088 | 0.79 | CYP3A4 (0.46) | CYP3A4MAPK1CYP2A6AHRCXCR1 | |
| SCHEMBL23273230 | 0.77 | HTR2A (0.34) | CYP3A4MAPK1CYP2A6TDP1CYP1A2 | |
| SCHEMBL1561688 | 0.72 | CYP3A4 (0.35) | CYP3A4MAPK1CYP2A6AHRCXCR1 | |
| SCHEMBL11595170 | 0.72 | CYP3A4 (0.59) | CYP3A4MAPK1CXCR1CXCR2TDP1 | |
| SCHEMBL7615955 | 0.72 | CYP3A4 (0.35) | CYP3A4MAPK1CYP2A6AHRCXCR1 | |
| SCHEMBL19830027 | 0.72 | CYP3A4 (0.36) | CYP3A4MAPK1CYP2A6AHRHTR2A | |
| SCHEMBL10990892 | 0.72 | TSHR (0.39) | CYP3A4MAPK1AHRTDP1TSHR | |
| SCHEMBL4448667 | 0.72 | ALDH1A1 (0.36) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010039349-A1 | Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds | SHELL OIL COMPANY | 2001-11-08 | — | — | US | claimed |
| US-4347390-A | Process for producing 1-bromo-3,5-dichlorobenzene | ISHIHARA SANGYO KAISHA LTD. | 1982-08-31 | — | — | US | claimed |
| US-9115151-B2 | Substituted 2,10-dihydro-9-oxa-1,2,4A-triazaphenanthren-3-ones and uses thereof | ABBVIE INC. (US) | 2015-08-25 | — | — | US | disclosed |
| US-9115151-B2 | Substituted 2,10-dihydro-9-oxa-1,2,4A-triazaphenanthren-3-ones and uses thereof | ABBVIE INC. (US) | 2015-08-25 | — | — | US | disclosed |
| CN-102712704-B | Three and four atom bridged dicarbonate compounds as internal donors in catalysts for polypropylene manufacture | DOW GLOBAL TECHNOLOGIES INC | 2015-01-07 | — | — | CN | disclosed |
| CN-102762603-B | Two atom bridged dicarbonate compounds as internal donors in catalysts for polypropylene manufacture | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-11-26 | — | — | CN | disclosed |
| EP-2507269-B1 | THREE AND FOUR ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE | GRACE W R & CO (US) | 2014-10-29 | — | — | EP | disclosed |
| EP-2507268-B1 | TWO ATOM BRIDGED DICARBONATE COMPOUNDS AS INTERNAL DONORS IN CATALYSTS FOR POLYPROPYLENE MANUFACTURE | GRACE W R & CO (US) | 2014-10-15 | — | — | EP | disclosed |
| US-20140206663-A1 | TRIAZINONE COMPOUNDS | WUXI APPTECH (SHANGHAI) CO., LTD. (CN) | 2014-07-24 | — | — | US | disclosed |
| US-20140206663-A1 | TRIAZINONE COMPOUNDS | WUXI APPTECH (SHANGHAI) CO., LTD. (CN) | 2014-07-24 | — | — | US | disclosed |
| WO-2014089904-A1 | TRIAZINONE COMPOUNDS | ABBVIE INC. (US) | 2014-06-19 | — | — | WO | disclosed |
| US-4414132-A | Olefin polymerization catalyst compositions and a process for the polymerization of olefins employing such compositions | SHELL OIL COMPANY (US) | 1983-11-08 | — | — | US | disclosed |
| EP-0019330-B1 | OLEFIN POLYMERIZATION CATALYST COMPOSITIONS AND A PROCESS FOR THE POLYMERIZATION OF OLEFINS EMPLOYING SUCH COMPOSITIONS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-08-31 | — | — | EP | disclosed |
| US-4400302-A | TITANIUM HALIDE, ALKYL MAGNESIUM | SHELL OIL COMPANY (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0046859-B1 | PROCESS FOR THE PREPARATION OF 1-BROMO-3,5-DICHLOROBENZENE | BASF Aktiengesellschaft (DE) | 1983-07-06 | — | — | EP | disclosed |
| US-4368340-A | VAPOR PHASE CHLORINATION OF 1,3,5-TRIHALOBENZENE HAVING BROMINE ATOMS | ISHIHARA SANGYO KAISHA LTD. (JP) | 1983-01-11 | — | — | US | disclosed |
| EP-0063066-A1 | Process for the isomerization of bromohalogen benzenes | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1982-10-20 | — | — | EP | disclosed |
| US-4347390-A | Process for producing 1-bromo-3,5-dichlorobenzene | ISHIHARA SANGYO KAISHA LTD. | 1982-08-31 | — | — | US | disclosed |
| EP-0046859-A1 | Process for the preparation of 1-bromo-3,5-dichlorobenzene | BASF Aktiengesellschaft (DE) | 1982-03-10 | — | — | EP | disclosed |
| EP-0019330-A1 | Olefin polymerization catalyst compositions and a process for the polymerization of olefins employing such compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206663-A1 | TRIAZINONE COMPOUNDS | THPO, IL5, CYP11B2 | CYP3A4 21/4885MAPK1 1200/4885CYP2A6 60/4885 |
| US-20010039349-A1 | Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds | AHR, PAH, HRH3 | CYP3A4 125/4885MAPK1 2544/4885CYP2A6 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.