Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 4/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28124931 | 0.83 | KCNN4 (0.46) | KCNN4KIF11TAAR1TDP1CYP1A2 | |
| SCHEMBL1225190 | 0.83 | KCNN4 (0.46) | KCNN4KIF11TAAR1TDP1CYP1A2 | |
| Hydrochloric Acid SCHEMBL2810585 | 0.81 | KCNN4 (0.44) | KCNN4KIF11TAAR1TDP1CYP1A2 | |
| SCHEMBL4750696 | 0.81 | KCNN4 (0.44) | KCNN4KIF11TAAR1TDP1CYP1A2 | |
| SCHEMBL27813866 | 0.80 | KCNN4 (0.48) | KCNN4KIF11TAAR1CYP2D6TSHR | |
| SCHEMBL27798200 | 0.79 | TAAR1 (0.45) | KCNN4KIF11TAAR1CYP1A2CYP2C19 | |
| SCHEMBL1455173 | 0.79 | TAAR1 (0.45) | KCNN4KIF11TAAR1CYP1A2CYP2C19 | |
| SCHEMBL453393 | 0.79 | KCNN4 (0.52) | KCNN4KIF11TAAR1CYP1A2CYP2C9 | |
| Ethylene Glycol SCHEMBL9403955 | 0.79 | KCNN4 (0.52) | KCNN4KIF11TAAR1TDP1CYP1A2 | |
| SCHEMBL1524876 | 0.77 | KIF11 (0.54) | KCNN4KIF11TAAR1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920342-B2 | Process for the preparation of Droxidopa | DIVI'S LABORATORIES LIMITED | 2018-03-20 | — | — | US | disclosed |
| US-20170335357-A1 | PROCESS FOR THE PREPARATION OF DROXIDOPA | DIVI'S LABORATORIES LIMITED (IN) | 2017-11-23 | — | — | US | disclosed |
| CN-1182076-A | Reclamation of bisphenol tars as feedstock in synthesis of aminophenylhydroxyphenylalkanes | GEN ELECTRIC (US) | 1998-05-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170335357-A1 | PROCESS FOR THE PREPARATION OF DROXIDOPA | DAO, DDO, DNPEP | KCNN4 2297/4885KIF11 3711/4885TAAR1 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.