SCHEMBL4750696

SCHEMBL4750696

NC(O)(CCO)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.44
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KIF11 P52732 4/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
KDM4E B2RXH2 2/20 0.37
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
PTPN1 P18031 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8370180 0.82 KCNN4 (0.44) KCNN4CYP1A2CYP2C9CYP2C19KIF11
SCHEMBL19614367 0.81 KCNN4 (0.48) KCNN4CYP1A2CYP2C9CYP2C19KIF11
Hydrochloric Acid SCHEMBL326016 0.80 SMN1; SMN2 (0.46) KCNN4CYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL28986870 0.80 KCNN4 (0.42) KCNN4CYP1A2CYP2C9CYP2C19KIF11
SCHEMBL28124931 0.79 KCNN4 (0.46) KCNN4CYP1A2CYP2C9CYP2C19KIF11
SCHEMBL1225190 0.79 KCNN4 (0.46) KCNN4CYP1A2CYP2C9CYP2C19KIF11
SCHEMBL8375787 0.78 CYP1A2 (0.47) KCNN4CYP1A2CYP2C9CYP2C19KIF11
Hydrochloric Acid SCHEMBL2810585 0.77 KCNN4 (0.44) KCNN4CYP1A2CYP2C9CYP2C19KIF11
SCHEMBL11088106 0.77 HIF1A (0.42) KCNN4CYP1A2CYP2C19KIF11ALDH1A1
SCHEMBL11212708 0.76 CYP2C19 (0.43) KCNN4CYP1A2CYP2C9CYP2C19KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105131236-B A kind of polyurethane aqueous dispersion body and the preparation method and application thereof of plant oil modified side chain ketocarbonyl-containing 华南理工大学 2018-09-14 CN disclosed
WO-2008125599-A1 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS SMITHKLINE BEECHAM CORPORATION (US) 2008-10-23 WO disclosed
WO-2003002635-A1 POLYORGANOSILOXANE WITH ACRYLATE FUNCTIONALITIES, METHOD FOR PRODUCTION THEREOF AND SILICONE COMPOSITION CONTAINING THE SAME RHODIA CHIMIE (FR) 2003-01-09 WO disclosed
US-5274089-A A estra-1,3,5(10)-triene derivative THE UPJOHN COMPANY (US) 1993-12-28 US disclosed
EP-0401627-A2 Copolymers with hydroxy groups, process for their preparation and their usage as binder BAYER AG (DE) 1990-12-12 EP disclosed
EP-0260121-A2 Inosose derivatives, production and use thereof Takeda Chemical Industries, Ltd. (JP) 1988-03-16 EP disclosed