Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534857 | 0.89 | PTGDR2 (0.39) | PTGDR2HPGD | |
| SCHEMBL3779879 | 0.83 | PTGDR2 (0.64) | PTGDR2 | |
| SCHEMBL534794 | 0.82 | PTGDR2 (0.51) | PTGDR2CCNE2CCNE1CDK2 | |
| SCHEMBL3772684 | 0.81 | PTGDR2 (0.54) | PTGDR2CYP1A2CYP2C9KMT2ADHFR | |
| SCHEMBL20943426 | 0.80 | PTGDR2 (0.54) | PTGDR2MEN1HPGDKMT2A | |
| SCHEMBL534920 | 0.80 | PTGDR2 (0.49) | PTGDR2HPGD | |
| SCHEMBL534080 | 0.80 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL534009 | 0.79 | PTGDR2 (0.32) | PTGDR2 | |
| SCHEMBL534858 | 0.77 | PTGDR2 (0.39) | PTGDR2 | |
| SCHEMBL3778460 | 0.76 | PTGDR2 (0.66) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017199903-A1 | CRYSTAL OF QUINOLINE DERIVATIVE | 帝人ファーマ株式会社 | 2017-11-23 | — | — | WO | disclosed |