Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534920 | 0.89 | PTGDR2 (0.49) | PTGDR2CYP2A6ARHPGDSMN1; SMN2 | |
| SCHEMBL19614973 | 0.89 | PTGDR2 (0.44) | PTGDR2HPGD | |
| SCHEMBL534858 | 0.89 | PTGDR2 (0.39) | PTGDR2CYP2A6AR | |
| SCHEMBL534009 | 0.88 | PTGDR2 (0.32) | PTGDR2SMN1; SMN2 | |
| SCHEMBL534813 | 0.84 | PTGDR2 (0.58) | PTGDR2 | |
| SCHEMBL534686 | 0.83 | PTGDR2 (0.49) | PTGDR2HPGDSMN1; SMN2 | |
| SCHEMBL533986 | 0.81 | AR (0.36) | AR | |
| SCHEMBL534921 | 0.78 | PTGDR2 (0.49) | PTGDR2CYP2A6AR | |
| SCHEMBL534010 | 0.77 | PTGDR2 (0.32) | PTGDR2SMN1; SMN2 | |
| SCHEMBL534794 | 0.76 | PTGDR2 (0.51) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129661-B1 | QUINOLINE DERIVATIVES AS CRTH2 RECEPTOR LIGANDS | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2012-02-08 | — | — | EP | claimed |