Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534857 | 0.89 | PTGDR2 (0.39) | PTGDR2ARCYP2A6HPGDSMN1; SMN2 | |
| SCHEMBL534921 | 0.88 | PTGDR2 (0.49) | PTGDR2ARCYP2A6PARP1GHSR | |
| SCHEMBL534794 | 0.87 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL534080 | 0.84 | PTGDR2 (0.51) | PTGDR2PARP1 | |
| SCHEMBL533926 | 0.84 | PTGDR2 (0.70) | PTGDR2 | |
| SCHEMBL534031 | 0.82 | PTGDR2 (0.59) | PTGDR2HPGD | |
| SCHEMBL534006 | 0.81 | PTGDR2 (0.50) | PTGDR2SMN1; SMN2 | |
| SCHEMBL534060 | 0.81 | AR (0.36) | PTGDR2ARSMN1; SMN2 | |
| SCHEMBL19614973 | 0.80 | PTGDR2 (0.44) | PTGDR2HPGD | |
| SCHEMBL534009 | 0.77 | PTGDR2 (0.32) | PTGDR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129661-B1 | QUINOLINE DERIVATIVES AS CRTH2 RECEPTOR LIGANDS | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2012-02-08 | — | — | EP | claimed |