Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | TKT | P29401 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27930055 | 0.82 | TRPV4 (0.43) | TRPV4L3MBTL1KCNH2MLYCDMAP4K4 | |
| SCHEMBL2307150 | 0.81 | TRPV4 (0.48) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL29456932 | 0.81 | TRPV4 (0.48) | TRPV4PDE10AL3MBTL1KCNH2MLYCD | |
| SCHEMBL1473684 | 0.81 | TRPV4 (0.48) | TRPV4PDE10AKCNH2MLYCDMAP4K4 | |
| SCHEMBL934659 | 0.81 | TRPV4 (0.48) | TRPV4PDE10AL3MBTL1KCNH2MLYCD | |
| SCHEMBL29827501 | 0.81 | TRPV4 (0.48) | TRPV4KCNH2MAP4K4PIK3CAMINK1 | |
| Hydrochloric Acid SCHEMBL4727672 | 0.78 | TRPV4 (0.46) | TRPV4PDE10AL3MBTL1KCNH2MLYCD | |
| SCHEMBL6140597 | 0.76 | TRPV4 (0.52) | TRPV4L3MBTL1KCNH2MLYCDMRGPRX4 | |
| SCHEMBL15774236 | 0.74 | TRPV4 (0.50) | TRPV4L3MBTL1KCNH2MLYCDMRGPRX4 | |
| SCHEMBL29418677 | 0.74 | L3MBTL1 (0.57) | TRPV4L3MBTL1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198812-A2 | PROCESS FOR THE MANUFACTURE OF 2-SUBSTITUTED-5-(1-METHYLTHIO)ALKYLPYRIDINES | SOLVAY SA (BE) | 2017-11-23 | — | — | WO | disclosed |
| WO-2017198812-A2 | PROCESS FOR THE MANUFACTURE OF 2-SUBSTITUTED-5-(1-METHYLTHIO)ALKYLPYRIDINES | SOLVAY SA (BE) | 2017-11-23 | — | — | WO | disclosed |