Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 6/20 | 0.51 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | CTSK | P43235 | 6/20 | 0.50 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21074226 | 1.00 | ATM (0.52) | ATMELANECTSSCTSLCTSK | |
| SCHEMBL19615920 | 1.00 | ATM (0.52) | ATMELANECTSSCTSLCTSK | |
| SCHEMBL19615767 | 0.87 | ELANE (0.53) | ATMELANECTSSCTSLCTSK | |
| SCHEMBL19615891 | 0.87 | ELANE (0.53) | ATMELANECTSSCTSLCTSK | |
| SCHEMBL21074209 | 0.87 | ELANE (0.53) | ATMELANECTSSCTSLCTSK | |
| SCHEMBL18157218 | 0.86 | ATM (0.57) | ATMELANECTSSCTSLCTSK | |
| SCHEMBL19615435 | 0.86 | CTSS (0.52) | ATMELANECTSSCTSLCTSK | |
| SCHEMBL21074225 | 0.86 | CTSS (0.52) | ATMELANECTSSCTSLCTSK | |
| SCHEMBL19615432 | 0.86 | CTSS (0.52) | ATMELANECTSSCTSLCTSK | |
| SCHEMBL6841165 | 0.83 | CTSS (0.61) | ATMELANECTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458584-B1 | FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN | CONSEJO SUPERIOR INVESTIGACION (ES) | 2021-07-07 | — | — | EP | disclosed |
| US-10683493-B2 | Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2020-06-16 | — | — | US | disclosed |
| US-20190194638-A1 | FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN | TECHNICAL UNIVERSITY OF DARMSTADT (DE) | 2019-06-27 | — | — | US | disclosed |
| EP-3458584-A1 | FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN | Consejo Superior De Investigaciones Científicas (ES) | 2019-03-27 | — | — | EP | disclosed |
| WO-2017198717-A1 | FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194638-A1 | FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN | ALDOA, TALDO1, DERA | ATM 4118/4885ELANE 3080/4885CTSS 3245/4885 |
| US-10683493-B2 | Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein | ALDOA, TALDO1, DERA | ATM 4118/4885ELANE 3080/4885CTSS 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.