SCHEMBL21074209

SCHEMBL21074209

CC(C)C(C(=O)C(=O)O)C(O)[C@@H](C)NC(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.53
PRTN3 P24158 2/20 0.50
ATM Q13315 1/20 0.50
CTSS P25774 5/20 0.49
CTSL P07711 4/20 0.49
CTSK P43235 5/20 0.48
CTRB1 P17538 2/20 0.47
CTSB P07858 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19615891 1.00 ELANE (0.53) ELANEPRTN3ATMCTSSCTSL
SCHEMBL19615767 1.00 ELANE (0.53) ELANEPRTN3ATMCTSSCTSL
SCHEMBL19615652 0.87 ATM (0.52) ELANEPRTN3ATMCTSSCTSL
SCHEMBL21074226 0.87 ATM (0.52) ELANEPRTN3ATMCTSSCTSL
SCHEMBL19615920 0.87 ATM (0.52) ELANEPRTN3ATMCTSSCTSL
SCHEMBL18157218 0.86 ATM (0.57) ELANEPRTN3ATMCTSSCTSL
SCHEMBL21074225 0.84 CTSS (0.52) ELANEPRTN3ATMCTSSCTSL
SCHEMBL19615435 0.84 CTSS (0.52) ELANEPRTN3ATMCTSSCTSL
SCHEMBL19615432 0.84 CTSS (0.52) ELANEPRTN3ATMCTSSCTSL
SCHEMBL14704026 0.82 ATM (0.61) ELANEPRTN3ATMCTSSCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3458584-B1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN CONSEJO SUPERIOR INVESTIGACION (ES) 2021-07-07 EP disclosed
US-10683493-B2 Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) 2020-06-16 US disclosed
US-20190194638-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN TECHNICAL UNIVERSITY OF DARMSTADT (DE) 2019-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194638-A1 FUSION PROTEINS COMPRISING AN ALDOLASE ENZYME JOINED TO A MALTOSE BINDING PROTEIN ALDOA, TALDO1, DERA ELANE 3080/4885PRTN3 2917/4885ATM 4118/4885
US-10683493-B2 Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein ALDOA, TALDO1, DERA ELANE 3080/4885PRTN3 2917/4885ATM 4118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.