Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28127724 | 0.98 | TSHR (0.55) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL12926133 | 0.84 | TSHR (0.58) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL19299334 | 0.82 | TSHR (0.56) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL27994582 | 0.82 | TSHR (0.60) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL889856 | 0.82 | TSHR (0.60) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL28695618 | 0.82 | TSHR (0.60) | TSHRALDH1A1KMT2AMEN1LMNA | |
| Dimethyl Succinate SCHEMBL28327672 | 0.80 | TSHR (0.65) | TSHRALDH1A1KMT2AMEN1LMNA | |
| Ammonia Solution, Strong SCHEMBL3920826 | 0.80 | TSHR (0.57) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL25021755 | 0.78 | TSHR (0.55) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL6762562 | 0.78 | TSHR (0.55) | TSHRALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250186543-A1 | CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL, INC. | 2025-06-12 | — | — | US | disclosed |
| CN-118324867-A | Novel cyclosporin derivatives and uses thereof | 美国科技环球有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-109476705-B | Novel cyclosporin derivatives and uses thereof | 美国科技环球有限公司 | 2024-02-27 | — | — | CN | disclosed |
| US-11827586-B2 | Method for producing amino acid aminoalkyl ester or inorganic acid salt thereof | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-11-28 | — | — | US | disclosed |
| US-20220331397-A1 | CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. | 2022-10-20 | — | — | US | disclosed |
| CN-114891070-A | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-107835818-B | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-04-29 | — | — | CN | disclosed |
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| US-20190151403-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. | 2019-05-23 | — | — | US | disclosed |
| EP-3458470-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2019-03-27 | — | — | EP | disclosed |
| CN-109476705-A | novel cyclosporin derivatives and use thereof | 美国科技环球有限公司 | 2019-03-15 | — | — | CN | disclosed |
| WO-2017200984-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250186543-A1 | CYCLOSPORIN DERIVATIVES AND USES THEREOF | MALT1, MTPN, MYLK2 | TSHR 3832/4885ALDH1A1 1876/4885KMT2A 4548/4885 |
| US-20220331397-A1 | CYCLOSPORIN DERIVATIVES AND USES THEREOF | MALT1, MTPN, MYLK2 | TSHR 3832/4885ALDH1A1 1876/4885KMT2A 4548/4885 |
| US-20190151403-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | MALT1, MYLK2, FKBP1B | TSHR 4178/4885ALDH1A1 2805/4885KMT2A 4599/4885 |
| US-11827586-B2 | Method for producing amino acid aminoalkyl ester or inorganic acid salt thereof | SLC6A15, SLC6A19, ALAD | TSHR 3390/4885ALDH1A1 1123/4885KMT2A 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.