Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.73 |
| ▸ | KDR | P35968 | 4/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19616599 | 0.90 | RAB9A (0.73) | HDAC6KDRL3MBTL1TDP1GAA | |
| SCHEMBL30063285 | 0.88 | KMT2A (0.77) | HDAC6KDRL3MBTL1TDP1GAA | |
| SCHEMBL19748126 | 0.88 | KMT2A (0.77) | HDAC6KDRL3MBTL1TDP1GAA | |
| SCHEMBL16456332 | 0.86 | HDAC6 (0.77) | HDAC6KDRL3MBTL1TDP1GAA | |
| SCHEMBL29655132 | 0.86 | HDAC6 (0.77) | HDAC6KDRL3MBTL1TDP1GAA | |
| SCHEMBL16456367 | 0.85 | POLB (0.73) | HDAC6KDRL3MBTL1TDP1GAA | |
| SCHEMBL29647754 | 0.85 | HDAC6 (1.00) | HDAC6KDRL3MBTL1TDP1GAA | |
| SCHEMBL15270551 | 0.85 | HDAC6 (0.79) | HDAC6KDRL3MBTL1TDP1GAA | |
| SCHEMBL19631488 | 0.85 | HDAC6 (1.00) | HDAC6KDRL3MBTL1TDP1GAA | |
| SCHEMBL6260903 | 0.84 | KDR (1.00) | HDAC6KDRL3MBTL1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346563-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | UNIV TAIPEI MEDICAL (TW) | 2025-11-13 | — | — | US | disclosed |
| US-11427544-B2 | Histone deacetylase 6 inhibitors and use thereof | TAIPEI MEDICAL UNIVERSITY (TW) | 2022-08-30 | — | — | US | disclosed |
| US-20220251043-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | TAIPEI MEDICAL UNIVERSITY (TW) | 2022-08-11 | — | — | US | disclosed |
| EP-3458444-B1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | UNIV TAIPEI MEDICAL (TW) | 2022-06-22 | — | — | EP | disclosed |
| EP-3458444-B1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | UNIV TAIPEI MEDICAL (TW) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021013163-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | TAIPEI MEDICAL UNIVERSITY (CN) | 2021-01-28 | — | — | WO | disclosed |
| US-20190284141-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | DCB-USA LLC (US) | 2019-09-19 | — | — | US | disclosed |
| US-20190284141-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | DCB-USA LLC (US) | 2019-09-19 | — | — | US | disclosed |
| EP-3458444-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | DCB-USA LLC (US) | 2019-03-27 | — | — | EP | disclosed |
| WO-2017200966-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | DCB-USA LLC (US) | 2017-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190284141-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND USE THEREOF | HDAC1, HDAC11, HDAC7 | HDAC6 7/4885KDR 4795/4885L3MBTL1 3557/4885 |
| US-20250346563-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | HDAC1, HDAC3, HDAC5 | HDAC6 4/4885KDR 4807/4885L3MBTL1 2594/4885 |
| US-20220251043-A1 | HISTONE DEACETYLASE 6 INHIBITORS AND METHOD FOR TREATING NEUROPATHIC PAIN | HDAC1, HDAC3, HDAC2 | HDAC6 9/4885KDR 4819/4885L3MBTL1 2793/4885 |
| US-11427544-B2 | Histone deacetylase 6 inhibitors and use thereof | HDAC1, HDAC11, HDAC7 | HDAC6 7/4885KDR 4795/4885L3MBTL1 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.