Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.71 |
| ▸ | KDR | P35968 | 4/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18668668 | 0.88 | HDAC6 (0.73) | POLBKMT2AHDAC6KDRTDP1 | |
| SCHEMBL24522646 | 0.86 | HDAC6 (0.74) | POLBKMT2AHDAC6KDRTDP1 | |
| SCHEMBL19631308 | 0.86 | KMT2A (0.71) | POLBKMT2AHDAC6KDRTDP1 | |
| SCHEMBL19616631 | 0.85 | HDAC6 (0.73) | POLBKMT2AHDAC6KDRTDP1 | |
| SCHEMBL16456332 | 0.85 | HDAC6 (0.77) | POLBKMT2AHDAC6KDRTDP1 | |
| SCHEMBL29655132 | 0.85 | HDAC6 (0.77) | POLBKMT2AHDAC6KDRTDP1 | |
| SCHEMBL19616636 | 0.85 | KMT2A (0.70) | POLBKMT2AHDAC6KDRTDP1 | |
| SCHEMBL18668657 | 0.84 | KDR (0.70) | POLBKMT2AHDAC6KDRTDP1 | |
| SCHEMBL19617433 | 0.84 | HDAC6 (0.74) | POLBKMT2AHDAC6KDRTDP1 | |
| SCHEMBL19631488 | 0.83 | HDAC6 (1.00) | POLBKMT2AHDAC6KDRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111519204-B | Method for preparing N- (5-chloro-8-quinolyl) benzamide compound by adopting electrochemical microchannel reaction device | 南京工业大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-111423372-B | Method for preparing N- (5-hydroxyquinoline-8-yl) benzamide compound by electrochemical microchannel reaction device | 南京工业大学 | 2021-04-27 | — | — | CN | disclosed |
| CN-111519204-A | Method for preparing N- (5-chloro-8-quinolyl) benzamide compound by adopting electrochemical microchannel reaction device | 南京工业大学 | 2020-08-11 | — | — | CN | disclosed |
| CN-109320497-B | Method for preparing phenanthridinone compound by copper compound induction | 广州大学 | 2020-07-31 | — | — | CN | disclosed |
| CN-111423372-A | Method for preparing N- (5-hydroxyquinoline-8-yl) benzamide compound by electrochemical microchannel reaction device | 南京工业大学 | 2020-07-17 | — | — | CN | disclosed |
| CN-109320497-A | A method of phenanthridines ketone compounds are prepared by copper compound induction | 广州大学 | 2019-02-12 | — | — | CN | disclosed |
| US-9340549-B2 | Oxazolidinone compounds and derivatives thereof | AMGEN INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20150045368-A1 | OXAZOLIDINONE COMPOUNDS AND DERIVATIVES THEREOF | AMGEN INC. | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045368-A1 | OXAZOLIDINONE COMPOUNDS AND DERIVATIVES THEREOF | TNKS1BP1, TNKS, TBKBP1 | POLB 172/4885KMT2A 2435/4885HDAC6 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.