Ethylene

Ethylene

SCHEMBL19616645

C=C.C=C.C=C.O=C(OCC(CO)OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
PRKCA P17252 1/20 0.57
PTPN1 P18031 2/20 0.50
POLB P06746 1/20 0.49
HSD17B10 Q99714 1/20 0.49
SERPINE1 P05121 1/20 0.49
TDP1 Q9NUW8 2/20 0.47
TSHR P16473 2/20 0.47
TP53 P04637 1/20 0.47
ADRB2 P07550 2/20 0.47
ADRB1 P08588 2/20 0.47
ADRB3 P13945 2/20 0.47
KMT2A Q03164 2/20 0.46
MAPK1 P28482 1/20 0.46
HIF1A Q16665 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
MEN1 O00255 1/20 0.45
LMNA P02545 2/20 0.45
SLC1A5 Q15758 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3181495 0.97 ALDH1A1 (0.61) ALDH1A1PRKCAPTPN1POLBHSD17B10
SCHEMBL29964300 0.97 ALDH1A1 (0.61) ALDH1A1PRKCAPTPN1POLBHSD17B10
Propene SCHEMBL1270277 0.91 PRKCA (0.52) ALDH1A1PRKCAPTPN1POLBHSD17B10
Tribenzoin SCHEMBL28609 0.88 ALDH1A1 (0.67) ALDH1A1PRKCAPTPN1SERPINE1TDP1
SCHEMBL17557410 0.86 PRKCA (0.49) ALDH1A1PRKCAPTPN1POLBHSD17B10
SCHEMBL872053 0.84 TSHR (0.59) ALDH1A1PRKCATDP1TSHRTP53
SCHEMBL14569202 0.84 ALDH1A1 (0.62) ALDH1A1PRKCAPTPN1POLBHSD17B10
SCHEMBL7292206 0.83 ALDH1A1 (0.61) ALDH1A1PRKCAPTPN1POLBHSD17B10
SCHEMBL13599580 0.83 ALDH1A1 (0.61) ALDH1A1PRKCAPTPN1SERPINE1TDP1
SCHEMBL3417176 0.83 MEN1 (0.60) ALDH1A1PRKCAPOLBTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190276697-A1 IMPROVED ACRYLIC LIQUID APPLIED SOUND DAMPERS EASTMAN CHEMICAL COMPANY (US) 2019-09-12 US disclosed
EP-3458533-A1 IMPROVED ACRYLIC LIQUID APPLIED SOUND DAMPERS Eastman Chemical Company (US) 2019-03-27 EP disclosed
WO-2017200811-A1 IMPROVED ACRYLIC LIQUID APPLIED SOUND DAMPERS EASTMAN CHEMICAL COMPANY (US) 2017-11-23 WO disclosed